Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20438154 | 0.83 | BUB1 (0.38) | BUB1BCHEHTR6KDM4EMAPT | |
| SCHEMBL16653120 | 0.80 | TK1 (0.43) | BUB1MAPK1 | |
| SCHEMBL15616807 | 0.79 | LMNA (0.46) | BUB1KDM4EMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4156346 | 0.79 | TYMP (0.45) | BUB1BCHEKDM4EMAPTTHRB | |
| SCHEMBL5334520 | 0.79 | TYMP (0.45) | BUB1BCHEKDM4EMAPTTHRB | |
| SCHEMBL8235112 | 0.79 | SQOR (0.49) | BUB1BCHE | |
| SCHEMBL31094710 | 0.78 | CYP1A2 (0.38) | BUB1BCHEKDM4EMAPTTHRB | |
| SCHEMBL7834254 | 0.76 | THRB (0.34) | BUB1BCHEKDM4EMAPTTHRB | |
| SCHEMBL7821308 | 0.76 | BUB1 (0.34) | BUB1BCHEHTR6KDM4EMAPT | |
| SCHEMBL18447676 | 0.75 | KIT (0.42) | BCHEMAPTL3MBTL1SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11178873-B2 | Cyclic N-carboxamide compounds useful as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-10653148-B2 | — | — | 2020-05-19 | — | — | US | disclosed |
| US-20180213788-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | FMC CORPORATION | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10653148-B2 | — | CYP1B1, CYP1A1, C5 | BUB1 1310/4885BCHE 3526/4885HTR6 3756/4885 |
| US-11178873-B2 | Cyclic N-carboxamide compounds useful as herbicides | CHRM2, NIT2, CHRM1 | BUB1 1772/4885BCHE 846/4885HTR6 2797/4885 |
| US-20180213788-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | CHRM2, NIT2, CHRM1 | BUB1 1772/4885BCHE 846/4885HTR6 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.