Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156346 | 1.00 | TYMP (0.45) | TYMPKMT2ACYP1A2GRIA1GRIA2 | |
| SCHEMBL16653120 | 0.83 | TK1 (0.43) | TYMPBUB1TK1 | |
| SCHEMBL8235112 | 0.81 | SQOR (0.49) | GRIA1GRIA2GRIA4GRIK5BUB1 | |
| SCHEMBL15616807 | 0.81 | LMNA (0.46) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL7834254 | 0.79 | THRB (0.34) | TYMPKMT2ACYP1A2GRIA1GRIA2 | |
| SCHEMBL7821308 | 0.79 | BUB1 (0.34) | KMT2ABUB1BCHETK1MAPT | |
| SCHEMBL20445101 | 0.79 | BUB1 (0.38) | KMT2ABUB1BCHEMAPTL3MBTL1 | |
| SCHEMBL20438154 | 0.79 | BUB1 (0.38) | BUB1BCHEMAPTL3MBTL1KDM4E | |
| SCHEMBL17123686 | 0.76 | KMT2A (0.49) | TYMPKMT2ACYP1A2GRIA1GRIA2 | |
| SCHEMBL31094710 | 0.74 | CYP1A2 (0.38) | KMT2ACYP1A2BUB1BCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122634-A2 | PYRIMIDINEDIONES AS TYROSINE KINASE INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2007-11-01 | — | — | WO | disclosed |