Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | GRK6 | P43250 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416075 | 0.85 | PKM (0.43) | PKMMAPTGAATDP1CYP1A2 | |
| SCHEMBL31709319 | 0.82 | L3MBTL1 (0.57) | PKMMAPTTDP1CYP1A2L3MBTL1 | |
| SCHEMBL4413652 | 0.82 | L3MBTL1 (0.57) | PKMMAPTTDP1CYP1A2L3MBTL1 | |
| SCHEMBL20448299 | 0.79 | PTPRC (0.50) | MAPTGAATDP1CYP1A2MCL1 | |
| SCHEMBL11091002 | 0.79 | ALDH1A1 (0.54) | MAPTGAATDP1CYP1A2L3MBTL1 | |
| SCHEMBL5416197 | 0.79 | ALDH1A1 (0.44) | PKMMAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL29093342 | 0.76 | CYP1A2 (0.46) | MAPTGAATDP1CYP1A2MCL1 | |
| SCHEMBL1660158 | 0.74 | CYP1A2 (0.61) | MAPTGAATDP1CYP1A2NPC1 | |
| SCHEMBL18791153 | 0.72 | POLB (0.46) | PKMMAPTTDP1L3MBTL1NPC1 | |
| SCHEMBL14273069 | 0.71 | LMNA (0.56) | MAPTTDP1CYP1A2L3MBTL1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276030-A1 | Pyranobenzothiophene derivatives to treat infection with hepatitis c virus | WYETH (US) | 2007-11-29 | — | — | US | disclosed |
| WO-2005016932-A1 | PYRANOBENZOTHIOPHENE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276030-A1 | Pyranobenzothiophene derivatives to treat infection with hepatitis c virus | LIPC, HAVCR2, GTF3C2 | PKM 1748/4885MAPT 2889/4885GAA 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.