Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 4/20 | 0.41 |
| ▸ | SKP1 | P63208 | 4/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9892864 | 0.83 | MAPT (0.54) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL20458171 | 0.79 | L3MBTL1 (0.48) | ALDH1A1MAPTGAAADORA1 | |
| SCHEMBL3710631 | 0.79 | L3MBTL1 (0.54) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL13257813 | 0.79 | L3MBTL1 (0.54) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL9107659 | 0.75 | MAPT (0.52) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL20458205 | 0.75 | RAB9A (0.50) | ALDH1A1HPGDMAPTGAA | |
| SCHEMBL20458247 | 0.74 | LMNA (0.40) | MAPTGAA | |
| SCHEMBL20458169 | 0.73 | L3MBTL1 (0.45) | ALDH1A1MAPTUSP30 | |
| SCHEMBL20458202 | 0.72 | ATAD2 (0.47) | ALDH1A1HSD17B10HPGDTSHRMAPT | |
| SCHEMBL20458229 | 0.71 | CNR2 (0.39) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |