Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088067 | 0.91 | MAPT (0.50) | TSHRLMNADAOALDH1A1TDP1 | |
| SCHEMBL4918857 | 0.89 | SNCA (0.44) | TSHRLMNADAOALDH1A1TDP1 | |
| SCHEMBL11293646 | 0.80 | MAPT (0.47) | TSHRLMNAALDH1A1TDP1MEN1 | |
| SCHEMBL11244582 | 0.78 | MAPT (0.49) | LMNAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12553301 | 0.76 | ALDH1A1 (0.41) | TSHRLMNAALDH1A1TDP1HSD17B10 | |
| SCHEMBL6993736 | 0.74 | MEN1 (0.41) | TSHRLMNADAOALDH1A1TDP1 | |
| SCHEMBL10432083 | 0.72 | KIF11 (0.43) | TSHRLMNADAOALDH1A1TDP1 | |
| SCHEMBL311661 | 0.70 | S100A4 (0.68) | TSHRLMNADAOALDH1A1TDP1 | |
| SCHEMBL9488144 | 0.69 | CYP3A4 (0.49) | TSHRLMNAALDH1A1TDP1HSD17B10 | |
| SCHEMBL10311827 | 0.69 | TSHR (0.48) | TSHRLMNAALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106588890-B | Antiviral compounds | 吉利德制药有限责任公司 | 2020-11-27 | — | — | CN | disclosed |
| EP-3626716-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-3309157-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2019-09-04 | — | — | EP | disclosed |
| US-9981955-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2018-05-29 | — | — | US | disclosed |
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-02-02 | — | — | US | disclosed |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-02-02 | — | — | US | disclosed |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-02-02 | — | — | US | disclosed |
| US-4293628-A | Electrophotographic elements containing disazo compounds | RICOH CO., LTD. (JP) | 1981-10-06 | — | — | US | disclosed |
| US-4279981-A | Electrophotographic elements containing trisazo compounds | RICOH COMPANY, LTD. (JP) | 1981-07-21 | — | — | US | disclosed |
| US-4272598-A | STYRYL DYES | RICOH CO., LTD. (JP) | 1981-06-09 | — | — | US | disclosed |
| US-4268596-A | Electrophotographic element having 1,4-bis(azostyryl)-2,5 dimethoxy benzene compounds as photoconductors | RICOH COMPANY, LTD. (JP) | 1981-05-19 | — | — | US | disclosed |
| US-4260672-A | Electrophotographic sensitive element having a photoconductive disazo pigment | RICOH COMPANY, LTD. (JP) | 1981-04-07 | — | — | US | disclosed |
| US-4251613-A | LAMINATE OF CONDUCTIVE SUPPORT AND PHOTOSENSITIVE LAYER | RICOH COMPANY, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4251614-A | CARBAZOLE DERIVATIVES | RICOH COMPANY, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4247614-A | Electrophotographic element containing a disazo pigment | RICOH CO., LTD. (JP) | 1981-01-27 | — | — | US | disclosed |
| US-4242260-A | ELECTROGRAPHY; PHOTOCONDUCTIVITY | RICOH COMPANY, LTD. (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4229511-A | Electrophotography with uniform exposure for residual potential | RICOH COMPANY, LTD. (JP) | 1980-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | TSHR 4853/4885LMNA 1353/4885DAO 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.