SCHEMBL2047123

SCHEMBL2047123

C=C(CC(C)(CC)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.47
HIF1A Q16665 1/20 0.47
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAOA P21397 6/20 0.39
MAOB P27338 6/20 0.39
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7172775 0.83 CYP2C19 (0.44) CYP2C19HIF1AALDH1A1MAOAMAOB
SCHEMBL29130605 0.82 CYP2C19 (0.41) CYP2C19HIF1AMAOAMAOB
SCHEMBL14921 0.81 TAAR1 (0.48) CYP2C19HIF1AALDH1A1MAOAMAOB
SCHEMBL3321479 0.80 MAOA (0.40) CYP2C19HIF1AALDH1A1MAPTMAOA
SCHEMBL5033208 0.79 MAOA (0.42) CYP2C19HIF1AALDH1A1MAPTMEN1
SCHEMBL296800 0.79 MAOA (0.42) CYP2C19HIF1AALDH1A1MAPTKMT2A
SCHEMBL5142143 0.79 CYP2C19 (0.38) CYP2C19HIF1AMAOAMAOB
SCHEMBL7169027 0.77 CYP2C19 (0.46) CYP2C19HIF1AALDH1A1MAPTMEN1
SCHEMBL7169023 0.77 CYP2C19 (0.46) CYP2C19HIF1AALDH1A1MAPTMEN1
SCHEMBL2399414 0.77 MAOA (0.47) CYP2C19HIF1AALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4201989-B1 POLYOLEFIN-BASED RESIN FOAMED PARTICLES AND POLYOLEFIN-BASED RESIN FOAM MOLDED ARTICLE KANEKA CORP (JP) 2025-08-06 EP disclosed
US-12378358-B2 Resin composition, molded body, and their application MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-08-05 US disclosed
CN-114075354-B Expanded polyolefin resin beads and expanded polyolefin resin molded article 株式会社钟化 2025-01-07 CN disclosed
US-20240182640-A1 Resin Composition, Molded Body, And Their Application MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-06-06 US disclosed
EP-4201989-A1 POLYOLEFIN-BASED RESIN FOAMED PARTICLES AND POLYOLEFIN-BASED RESIN FOAM MOLDED ARTICLE Kaneka Corporation (JP) 2023-06-28 EP disclosed
CN-110997794-B Polyethylene composition with tree growth retarder 陶氏环球技术有限责任公司 2023-06-13 CN disclosed
CN-111868154-B Polar organic copolymer and ultralow wettability carbon black composite 陶氏环球技术有限责任公司 2023-05-23 CN disclosed
CN-112739779-B Resin composition, molded article, and use thereof 三菱瓦斯化学株式会社 2023-02-21 CN disclosed
CN-109721868-B Method for producing thermoplastic resin extruded foam sheet 株式会社JSP 2022-12-23 CN disclosed
CN-110770289-B Polyolefin compositions 陶氏环球技术有限责任公司 2022-09-02 CN disclosed
US-20110250421-A1 EXTRUDED THERMOPLASTIC RESIN FOAM JSP CORPORATION (JP) 2011-10-13 US disclosed
EP-2374838-A1 Extruded thermoplastic resin foam JSP Corporation (JP) 2011-10-12 EP disclosed
US-7960443-B2 Extruded styrenic resin foam and method for producing the same JSP CORPORATION (JP) 2011-06-14 US disclosed
US-20100120941-A1 ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT TOKUYAMA DENTAL CORPORATION (JP) 2010-05-13 US disclosed
EP-2127631-A1 ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT Tokuyama Dental Corporation (JP) 2009-12-02 EP disclosed
US-20090069455-A1 Extruded styrenic resin foam and method for producing the same JSP CORPORATION (JP) 2009-03-12 US disclosed
EP-2033987-A1 Extruded styrenic resin foam and method for producing the same JSP Corporation (JP) 2009-03-11 EP disclosed
US-7041714-B2 Dental adhesive TOKUYAMA CORPORATION (JP) 2006-05-09 US disclosed
EP-1459726-A1 ADHESIVES FOR DENTAL USE TOKUYAMA CORPORATION (JP) 2004-09-22 EP disclosed
US-20040077746-A1 Adhesives for dental use TOKUYAMA CORPORATION (JP) 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077746-A1 Adhesives for dental use ICAM1, CDH1, VCAM1 CYP2C19 2534/4885HIF1A 1339/4885ALDH1A1 242/4885
US-20100120941-A1 ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT ICAM1, ITGB8, TRA2B CYP2C19 4826/4885HIF1A 1328/4885ALDH1A1 2057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.