SCHEMBL20484200

SCHEMBL20484200

C=COC=Cc1ccc(C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.47
NFE2L2 Q16236 5/20 0.45
CA1 P00915 1/20 0.42
CYP3A4 P08684 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40
TUBA1A Q71U36 1/20 0.40
TUBA1C Q9BQE3 1/20 0.40
TUBB6 Q9BUF5 1/20 0.40
TUBB2B Q9BVA1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL757522 0.86 RELA (0.54) RELANFE2L2CA1CYP3A4CYP2C9
Vinyl Ether SCHEMBL28561314 0.79 RELA (0.48) RELANFE2L2CYP3A4MAPTRAB9A
SCHEMBL20454571 0.77 ALDH1A1 (0.46) RELANFE2L2CA1CYP2C9ALOX5
SCHEMBL374820 0.77 ALDH1A1 (0.46) RELANFE2L2CA1CYP2C9ALOX5
SCHEMBL28658441 0.76 ALDH1A1 (0.44) RELANFE2L2CA1CYP2C9ALOX5
SCHEMBL5384402 0.75 RELA (0.58) RELANFE2L2CA1CYP3A4CYP2C9
SCHEMBL5384397 0.75 RELA (0.58) RELANFE2L2CA1CYP3A4CYP2C9
(E)-1,2-Di-P-Tolylethene SCHEMBL1793692 0.72 NFE2L2 (0.74) RELANFE2L2CA1CYP3A4CYP2C9
(E)-1,2-Di-P-Tolylethene SCHEMBL1305582 0.72 NFE2L2 (0.74) RELANFE2L2CA1CYP3A4CYP2C9
SCHEMBL318786 0.72 NFE2L2 (0.74) RELANFE2L2CA1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210129084-A1 INTEGRALLY ASYMMETRICAL, ISOPOROUS BLOCK COPOLYMER MEMBRANES IN FLAT SHEET GEOMETRY Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2021-05-06 US claimed
US-10835872-B2 Macroporous or mesoporous polymer films in hollow fiber geometry HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUER MATERIAL- UND KUESTENFORSCHUNG GMBH (DE) 2020-11-17 US claimed
EP-3541503-B1 INTEGRALLY ASYMMETICAL, ISOPOROUS BLOCK COPOLYMER MEMBRANES IN FLAT SHEET GEOMETRY HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2020-07-22 EP claimed
US-20190299166-A1 Macroporous Or Mesoporous Polymer Films In Hollow Fiber Geometry Helmholtz-Zentrum Geesthacht Zentrum fur Material-und Kustenforschung GmbH (GB) 2019-10-03 US claimed
EP-3398675-A1 MACROPOROUS OR MESOPOROUS POLYMER FILMS IN HOLLOW FIBER OR FLAT SHEET GEOMETRY Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-11-07 EP claimed
EP-3369474-A1 ISOPOROUS BLOCK COPOLYMER MEMBRANES IN FLAT SHEET GEOMETRY Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-09-05 EP claimed
US-20210129084-A1 INTEGRALLY ASYMMETRICAL, ISOPOROUS BLOCK COPOLYMER MEMBRANES IN FLAT SHEET GEOMETRY Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2021-05-06 US disclosed
US-10835872-B2 Macroporous or mesoporous polymer films in hollow fiber geometry HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUER MATERIAL- UND KUESTENFORSCHUNG GMBH (DE) 2020-11-17 US disclosed
EP-3541503-B1 INTEGRALLY ASYMMETICAL, ISOPOROUS BLOCK COPOLYMER MEMBRANES IN FLAT SHEET GEOMETRY HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2020-07-22 EP disclosed
US-20190299166-A1 Macroporous Or Mesoporous Polymer Films In Hollow Fiber Geometry Helmholtz-Zentrum Geesthacht Zentrum fur Material-und Kustenforschung GmbH (GB) 2019-10-03 US disclosed
EP-3369474-A1 ISOPOROUS BLOCK COPOLYMER MEMBRANES IN FLAT SHEET GEOMETRY Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-09-05 EP disclosed