SCHEMBL757522

SCHEMBL757522

Cc1ccc(C=COC=Cc2ccc(C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.54
NFE2L2 Q16236 5/20 0.52
CA1 P00915 1/20 0.48
CYP2A6 P11509 1/20 0.46
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
TUBB2A Q13885 1/20 0.45
TUBB8 Q3ZCM7 1/20 0.45
TUBA3E Q6PEY2 1/20 0.45
TUBA1A Q71U36 1/20 0.45
TUBA1C Q9BQE3 1/20 0.45
TUBB6 Q9BUF5 1/20 0.45
TUBB2B Q9BVA1 1/20 0.45
TUBB1 Q9H4B7 1/20 0.45
FBP1 P09467 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20484200 0.86 RELA (0.47) RELANFE2L2CA1CYP2A6TUBB4A
SCHEMBL5384402 0.82 RELA (0.58) RELANFE2L2CA1CYP2A6TUBB4A
SCHEMBL5384397 0.82 RELA (0.58) RELANFE2L2CA1CYP2A6TUBB4A
(E)-1,2-Di-P-Tolylethene SCHEMBL1305580 0.80 NFE2L2 (0.74) RELANFE2L2CA1CYP2A6TUBB4A
SCHEMBL318785 0.80 NFE2L2 (0.74) RELANFE2L2CA1CYP2A6TUBB4A
SCHEMBL318786 0.80 NFE2L2 (0.74) RELANFE2L2CA1CYP2A6TUBB4A
(E)-1,2-Di-P-Tolylethene SCHEMBL1793692 0.80 NFE2L2 (0.74) RELANFE2L2CA1CYP2A6TUBB4A
(E)-1,2-Di-P-Tolylethene SCHEMBL1305582 0.80 NFE2L2 (0.74) RELANFE2L2CA1CYP2A6TUBB4A
SCHEMBL2351512 0.78 RELA (0.48) RELANFE2L2CA1CYP2A6TUBB4A
SCHEMBL4270558 0.77 RELA (0.47) RELANFE2L2CA1CYP2A6TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6951705-B2 Polymers for photoresist compositions for microlithography E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-10-04 US claimed
US-20030211417-A1 Polymers for photoresist compositions for microlithography DUPONT ELECTRONICS, INC. 2003-11-13 US claimed
EP-1279069-A2 POLYMERS FOR PHOTORESIST COMPOSITIONS FOR MICROLITHOGRAPHY E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-01-29 EP claimed
WO-2001086352-A2 POLYMERS FOR PHOTORESIST COMPOSITIONS FOR MICROLITHOGRAPHY E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-11-15 WO claimed
US-20250206731-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2025-06-26 US disclosed
EP-4549430-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2025-05-07 EP disclosed
US-20250122178-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2025-04-17 US disclosed
EP-4317155-A1 COMPOUND, METHOD FOR PRODUCING SAME, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
US-20240018137-A1 COMPOUND, METHOD FOR PRODUCING SAME, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-18 US disclosed
EP-4063356-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2022-09-28 EP disclosed
US-20220283497-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2022-09-08 US disclosed
CN-113666883-A Method for synthesizing 4-vinyl isoxazole derivative 华南理工大学 2021-11-19 CN disclosed
EP-0828768-B1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION GOODRICH CO B F (US) 2001-04-18 EP disclosed
US-5985502-A TONERS WITH BINDER RESINS AND COLORS CANON KABUSHIKI KAISHA (JP) 1999-11-16 US disclosed
EP-0828768-A1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION The B.F. Goodrich Company (US) 1998-03-18 EP disclosed
US-5677405-A COPOLYMER OF NORBORNENE-TYPE MONOMER WHICH UNDERGOES ADDITION POLYMERIZATION AND CATIONICALLY POLYMERIZABLE MONOMER THE B.F. GOODRICH COMPANY (US) 1997-10-14 US disclosed
WO-1996037529-A1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION THE B.F. GOODRICH COMPANY (US) 1996-11-28 WO disclosed
US-5529889-A CONTAINING CYANINE COMPOUND CANON KABUSHIKI KAISHA (JP) 1996-06-25 US disclosed
EP-0559101-A1 Heat-developable photosensitive material and image forming method which uses the same CANON KABUSHIKI KAISHA (JP) 1993-09-08 EP disclosed
US-4560749-A ANTIBIOTICS, BACTERICIDES ELI LILLY AND COMPANY (US) 1985-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206731-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT H1-0, H1-3, H1-2 RELA 1537/4885NFE2L2 1246/4885CA1 525/4885
US-20250122178-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT H1-0, H1-2, CCNB2 RELA 2044/4885NFE2L2 109/4885CA1 1242/4885
US-20220283497-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT PAM, TMT1A, TAF1 RELA 2246/4885NFE2L2 2003/4885CA1 54/4885
US-20240018137-A1 COMPOUND, METHOD FOR PRODUCING SAME, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT F12, SEM1, NOX1 RELA 2474/4885NFE2L2 974/4885CA1 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.