SCHEMBL204910

SCHEMBL204910

CC1=C(C#N)C(c2ccccc2[N+](=O)[O-])C(C#N)=C(C)N1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CUL4A Q13619 1/20 0.64
KDM4E B2RXH2 5/20 0.58
KMT2A Q03164 5/20 0.56
ALDH1A1 P00352 4/20 0.56
MAPT P10636 3/20 0.56
ADORA3 P0DMS8 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
ABCC4 O15439 2/20 0.56
CACNA1F O60840 2/20 0.56
ABCB11 O95342 2/20 0.56
LMNA P02545 2/20 0.56
CYP1A2 P05177 2/20 0.56
ADORA2A P29274 2/20 0.56
ADORA1 P30542 2/20 0.56
OPRM1 P35372 2/20 0.56
SCN1A P35498 2/20 0.56
HTR2B P41595 2/20 0.56
CACNA1D Q01668 2/20 0.56
KCNH2 Q12809 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7265869 0.89 KDM4E (0.58) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL10693916 0.86 ADORA3 (0.78) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL3037209 0.82 KMT2A (0.50) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL11307558 0.82 ADORA3 (0.62) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL9765784 0.81 MAPT (0.57) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL13198586 0.80 CACNA1C (0.63) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL15571755 0.78 CUL4A (1.00) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL11357785 0.78 KDM4E (0.47) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL3326305 0.78 ALDH1A1 (0.52) CUL4AKDM4EKMT2AALDH1A1MAPT
SCHEMBL12727534 0.75 CACNA1C (0.58) CUL4AKDM4EKMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0578177-B1 Heat-resistant negative photoresist composition, photosensitive substrate, and process for forming negative pattern NITTO DENKO CORP (JP) 1997-03-05 EP claimed
EP-0578177-A2 Heat-resistant negative photoresist composition, photosensitive substrate, and process for forming negative pattern NITTO DENKO CORPORATION (JP) 1994-01-12 EP claimed
US-8778596-B2 Photosensitive resin composition, pattern forming material comprising the photosensitive resin composition, and pattern forming method and article using the photosensitive resin composition DAI NIPPON PRINTING CO., LTD. (JP) 2014-07-15 US disclosed
US-8742059-B2 Polymer precursor, high transparency polyimide precursor, polymer compound, resin composition and article using thereof DAI NIPPON PRINTING CO., LTD. (JP) 2014-06-03 US disclosed
US-8697332-B2 Base generator, photosensitive resin composition, pattern forming material comprising the photosensitive resin composition, pattern forming method using the photosensitive resin composition and products comprising the same DAI NIPPON PRINTING CO., LTD. (JP) 2014-04-15 US disclosed
US-20130309607-A1 PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, AND PATTERN FORMING METHOD AND ARTICLE USING THE PHOTOSENSITIVE RESIN COMPOSITION DAI NIPPON PRINTING CO., LTD. (JP) 2013-11-21 US disclosed
US-8476444-B2 Base generator DAI NIPPON PRINTING CO., LTD. (JP) 2013-07-02 US disclosed
US-20120183751-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-07-19 US disclosed
US-20120122033-A1 POLYMER PRECURSOR, HIGH TRANSPARENCY POLYIMIDE PRECURSOR, POLYMER COMPOUND, RESIN COMPOSITION AND ARTICLE USING THEREOF DAI NIPPON PRINTING CO., LTD. (JP) 2012-05-17 US disclosed
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-22 US disclosed
US-8088882-B2 Polymer precursor, high transparency polyimide precursor, polymer compound, resin composition and article using thereof DAI NIPPON PRINTING CO., LTD. (JP) 2012-01-03 US disclosed
EP-0271851-B1 LIGHT SENSITIVE MIXTURES FOR MAKING REPEATEDLY TONABLE LAYERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-10 EP disclosed
US-4904555-A Photosensitive composition for making repeatably tonable layers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-02-27 US disclosed
US-4859551-A Process for preparing positive and negative images using photohardenable electrostatic master E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-08-22 US disclosed
EP-0315121-A2 Process for preparing positive and negative images using photohardenable electrostatic master E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-10 EP disclosed
EP-0171748-B1 NEGATIVE-TONING IMAGING SYSTEM WITH RE-IMAGING CAPABILITY USING 4-(2'-NITROPHENYL)-1,4-DIHYDROPYRIDINE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-08 EP disclosed
US-4604340-A TACKY AND TONABLE WITH ACTINIC RADIATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-05 US disclosed
EP-0171748-A2 Negative-toning imaging system with re-imaging capability using 4-(2'-nitrophenyl)-1,4-Dihydropyridine compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-02-19 EP disclosed
US-4269933-A PHOTOLITHOGRAPHY; POSITIVE AND NEGATIVE IMAGES; POLYMERIZATION OF A UNSATURATED POLYESTER USING A PHOTOSENSITIVE FREE RADICAL SYSTEM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-26 US disclosed
US-4198242-A Photopolymerizable composition containing an o-nitroaromatic compound as photoinhibitor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME RER1, SUN2, REV1 CUL4A 2934/4885KDM4E 2434/4885KMT2A 1400/4885
US-20120183751-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME RER1, SUN2, POLR1G CUL4A 3159/4885KDM4E 1949/4885KMT2A 1328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.