SCHEMBL2050765

SCHEMBL2050765

Fc1ccc(F)c(-c2ccc[c]c2C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.36
PDK2 Q15119 2/20 0.35
GPBAR1 Q8TDU6 1/20 0.33
PDE3B Q13370 2/20 0.32
PDE3A Q14432 2/20 0.32
SLC9A1 P19634 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
CASP3 P42574 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2053315 0.87 PDK2 (0.35) PDK2GPBAR1PDE3BPDE3A
SCHEMBL15637439 0.83 GPR3 (0.33)
SCHEMBL2431241 0.82 HTR1A (0.33) PTPN1PDK2GPBAR1
SCHEMBL2431522 0.77 ENPP1 (0.39) PDK2
SCHEMBL17144532 0.77 HSD11B1 (0.33)
SCHEMBL2428521 0.77 HSD17B1 (0.34) PTPN1PDK2PDE3BPDE3A
SCHEMBL2430766 0.77 NT5E (0.41) PTPN1PDK2PDE3BPDE3A
SCHEMBL15637798 0.76
SCHEMBL2052438 0.76 PTPN1 (0.38) PTPN1PDK2PDE3BPDE3ASLC9A1
SCHEMBL2051089 0.76 HSD11B1 (0.38) PDK2GPBAR1PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 EP disclosed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 WO disclosed
WO-2013182433-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-12-12 WO disclosed
EP-2547687-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-01-23 EP disclosed
EP-2513067-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2012-10-24 EP disclosed
WO-2011073145-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2011-06-23 WO disclosed