Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509760 | 0.73 | SLC6A2 (0.39) | SMN1; SMN2HPGDTSHRHSD17B10TP53 | |
| SCHEMBL4756741 | 0.72 | CYP19A1 (0.40) | HPGDHSD17B10ALDH1A1MAPTCYP19A1 | |
| SCHEMBL38659921 | 0.72 | CYP19A1 (0.40) | HPGDHSD17B10ALDH1A1MAPTCYP19A1 | |
| SCHEMBL30307422 | 0.67 | ALDH1A1 (0.42) | SMN1; SMN2HPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL4499694 | 0.67 | KMT2A (0.35) | SMN1; SMN2HPGDTSHRALDH1A1KMT2A | |
| SCHEMBL64923 | 0.67 | ALDH1A1 (0.42) | SMN1; SMN2HPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL1599024 | 0.67 | CYP11B2 (0.47) | HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL29505892 | 0.67 | CYP11B2 (0.47) | HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11540740 | 0.67 | CYP11B2 (0.47) | HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11777181 | 0.66 | NPC1 (0.47) | SMN1; SMN2HPGDTSHRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143192-A1 | NEW TRIAZINOINDOLE COMPOUNDS | JANSSEN Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |
| US-11026426-B2 | Oxadiazole and phenol derivatives as antibacterial and/or herbicidal agents | NORTHERN ILLINOIS RESEARCH FOUNDATION (US) | 2021-06-08 | — | — | US | disclosed |
| US-20180271098-A1 | OXADIAZOLE AND PHENOL DERIVATIVES AS ANTIBACTERIAL AND/OR HERBICIDAL AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180271098-A1 | OXADIAZOLE AND PHENOL DERIVATIVES AS ANTIBACTERIAL AND/OR HERBICIDAL AGENTS | CMPK1, IPMK, ITPA | SMN1; SMN2 4256/4885TNKS2 1810/4885PARP2 3271/4885 |
| US-11026426-B2 | Oxadiazole and phenol derivatives as antibacterial and/or herbicidal agents | CBR3, AOC3, AHR | SMN1; SMN2 3949/4885TNKS2 4655/4885PARP2 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.