Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20510943 | 0.86 | CNR1 (0.47) | IDO1CNR1NOTUMCSF1R | |
| SCHEMBL380666 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3824245 | 0.79 | HDAC6 (0.48) | IDO1CNR1NOTUMCSF1RKDM4E | |
| SCHEMBL198093 | 0.77 | CNR1 (0.49) | IDO1CNR1SCN2ACSF1RKDM4E | |
| SCHEMBL9227395 | 0.77 | AHR (0.52) | IDO1CNR1NOTUMNPY5RKDM4E | |
| SCHEMBL11434632 | 0.77 | NT5E (0.57) | CNR1ALDH1A1 | |
| SCHEMBL7762234 | 0.77 | IDO1 (0.46) | IDO1CNR1NPY5R | |
| SCHEMBL16236283 | 0.77 | MAOA (0.50) | CNR1BRD4KDM4EALDH1A1GFER | |
| SCHEMBL7292924 | 0.77 | IDO1 (0.46) | IDO1CNR1KDM4EALDH1A1GAA | |
| SCHEMBL28553991 | 0.77 | METAP2 (0.46) | IDO1CNR1NOTUMCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939291-B2 | GRP94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2024-03-26 | — | — | US | disclosed |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS | 2022-01-27 | — | — | US | disclosed |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS | 2022-01-27 | — | — | US | disclosed |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2021-04-13 | — | — | US | disclosed |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2020-03-05 | — | — | US | disclosed |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2020-03-05 | — | — | US | disclosed |
| WO-2018081814-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS (US) | 2018-05-03 | — | — | WO | disclosed |
| WO-2018081814-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS (US) | 2018-05-03 | — | — | WO | disclosed |
| EP-2429994-A1 | BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS | Biolipox AB (SE) | 2012-03-21 | — | — | EP | disclosed |
| US-20120035217-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-02-09 | — | — | US | disclosed |
| CN-102348686-A | Bis aromatic compounds for use as ltc4 synthase inhibitors | BIOLIPOX AB (SE) | 2012-02-08 | — | — | CN | disclosed |
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| WO-2010103283-A1 | BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS | BIOLIPOX AB (SE) | 2010-09-16 | — | — | WO | disclosed |
| US-5378724-A | Insecticide. miticide, nematocide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| CN-1086513-A | Substituted 2-arylpyrroles | BAYER AG (DE) | 1994-05-11 | — | — | CN | disclosed |
| EP-0591806-A1 | Substituted 2-arylpyrroles | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035217-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | IDO1 210/4885CNR1 490/4885NOTUM 1207/4885 |
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | IDO1 393/4885CNR1 706/4885NOTUM 988/4885 |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | IDO1 4602/4885CNR1 3329/4885NOTUM 4163/4885 |
| US-11939291-B2 | GRP94 selective inhibitors and uses thereof | GRPR, HSP90B1, HSPE1 | IDO1 4602/4885CNR1 3329/4885NOTUM 4163/4885 |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | IDO1 4602/4885CNR1 3329/4885NOTUM 4163/4885 |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | GRPR, HSP90B1, HSPE1 | IDO1 4602/4885CNR1 3329/4885NOTUM 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.