Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20510943 | 0.84 | CNR1 (0.47) | IDO1NT5ECNR1 | |
| SCHEMBL18051426 | 0.83 | HDAC1 (0.39) | IDO1METAP2ACHENT5ECNR1 | |
| SCHEMBL380666 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL3824245 | 0.77 | HDAC6 (0.48) | IDO1NT5ECNR1 | |
| SCHEMBL237434 | 0.77 | IDO1 (0.56) | IDO1CNR1NPY5R | |
| SCHEMBL10035779 | 0.76 | HDAC1 (0.48) | IDO1ACHENT5ENISCHRAB9A | |
| SCHEMBL22109766 | 0.76 | ACHE (0.50) | IDO1METAP2ACHENPY5RNISCH | |
| SCHEMBL7292924 | 0.75 | IDO1 (0.46) | IDO1METAP2CNR1RAB9ANPC1 | |
| SCHEMBL11434632 | 0.75 | NT5E (0.57) | METAP2NT5ECNR1TSHR | |
| SCHEMBL16236283 | 0.75 | MAOA (0.50) | METAP2CNR1RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5415893-A | Dispersion of electrically conductive particles in a dispersing medium | DSM N.V. (NL) | 1995-05-16 | — | — | US | claimed |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS | 2022-01-27 | — | — | US | disclosed |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | UNIVERSITY OF KANSAS (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2020-03-05 | — | — | US | disclosed |
| CN-105986253-B | The plating application and its manufacturing method of excellent adhesion | 阿基里斯株式会社 | 2019-09-27 | — | — | CN | disclosed |
| WO-2018081814-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS (US) | 2018-05-03 | — | — | WO | disclosed |
| CN-105986253-A | Plated material with excellent marginal sealing performance and manufacturing method thereof | 阿基里斯株式会社 | 2016-10-05 | — | — | CN | disclosed |
| US-20140170405-A1 | PROCESSES FOR PREPARING CURED FILMS, THE RESULTING FILMS, AND PLASMA-INITIATED POLYMERIZABLE COMPOSITIONS | FUJIFILM CORPORATION (JP) | 2014-06-19 | — | — | US | disclosed |
| CN-101983257-B | Plated molded article and method for producing the same | ACHILLES CORP | 2013-05-15 | — | — | CN | disclosed |
| CN-101578392-B | Plated article and method of making same | ACHILLES CORP | 2011-04-13 | — | — | CN | disclosed |
| EP-0589529-A1 | Dispersion of electrically conductive particles in a dispersing medium | DSM N.V. (NL) | 1994-03-30 | — | — | EP | disclosed |
| EP-0587204-A1 | Method for the preparation of a polymeric shaped article containing an electrically conductive polymer | DSM N.V. (NL) | 1994-03-16 | — | — | EP | disclosed |
| US-5106690-A | Method for producing electrically conductive pigmentary composites | KERR-MCGEE CHEMICAL CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-5028481-A | Electrically conductive pigmentary composites | KERR-MCGEE CHEMICAL (US) | 1991-07-02 | — | — | US | disclosed |
| CN-1051049-A | ELECTRICALLY CONDUCTIVE PIGMENTARY COMPOSITES | KERR MC GEE CHEM CORP (US) | 1991-05-01 | — | — | CN | disclosed |
| EP-0424048-A2 | Electrically conductive pigmentary composites | KERR-McGEE CHEMICAL CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4795687-A | POLYTHIENYLENE, POLYPRYRROLE OR POLYANILINE MATERIAL PREPARED BY OXIDATION POLYMERIZATION | MITSUBISHI KASEI CORP. (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0261837-A2 | Electrically conductive material and a process for the preparation of same and secondary battery using the electrically conductive material | Sanyo Electric Co., Ltd (JP) | 1988-03-30 | — | — | EP | disclosed |
| US-4731311-A | Electrically conductive material and secondary battery using the electrically conductive material | SANYO ELECTRIC CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| EP-0219063-A2 | Process of manufacturing an electrically conductive material and a secondary battery using the electrically conductive material | Sanyo Electric Co., Ltd (JP) | 1987-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071271-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | IDO1 4602/4885METAP2 2041/4885ACHE 4323/4885 |
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | IDO1 4602/4885METAP2 2041/4885ACHE 4323/4885 |
| US-10975030-B2 | Grp94 selective inhibitors and uses thereof | GRPR, HSP90B1, HSPE1 | IDO1 4602/4885METAP2 2041/4885ACHE 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.