Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20512253 | 0.85 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL20512258 | 0.85 | NPSR1 (0.51) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL20512235 | 0.82 | CA1 (0.46) | KMT2AMEN1ALDH1A1HTTCA1 | |
| SCHEMBL12478115 | 0.77 | KMT2A (0.57) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL20512228 | 0.77 | EGFR (0.45) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL20512265 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1GAAHTT | |
| SCHEMBL20512232 | 0.74 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1GAAHTT | |
| SCHEMBL6801249 | 0.73 | ALDH1A1 (0.77) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL17793710 | 0.72 | KMT2A (0.61) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL20512274 | 0.72 | CYP19A1 (0.43) | KMT2AMEN1ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-12-13 | — | — | US | disclosed |
| US-10138252-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-11-27 | — | — | US | disclosed |
| US-20180305371-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-10-25 | — | — | US | disclosed |
| US-10087190-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | KMT2A 3125/4885MEN1 849/4885RAB9A 1707/4885 |
| US-20180305371-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | KMT2A 3125/4885MEN1 849/4885RAB9A 1707/4885 |
| US-10138252-B1 | Lactones | DHPS, FDPS, LSS | KMT2A 3286/4885MEN1 624/4885RAB9A 2028/4885 |
| US-10087190-B1 | Lactones | DHPS, FDPS, LSS | KMT2A 3286/4885MEN1 624/4885RAB9A 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.