Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20512258 | 0.82 | NPSR1 (0.51) | CYP19A1USP2MEN1KMT2ACYP1A2 | |
| SCHEMBL13040850 | 0.76 | CASR (0.40) | CYP19A1HKDC1USP2MEN1KMT2A | |
| SCHEMBL20512228 | 0.76 | EGFR (0.45) | CYP19A1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL20512261 | 0.75 | CA12 (0.52) | CYP19A1USP2MEN1KMT2ACYP1A2 | |
| SCHEMBL20512253 | 0.75 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL20512265 | 0.74 | ALDH1A1 (0.50) | USP2MEN1KMT2AALDH1A1CA12 | |
| SCHEMBL20512229 | 0.73 | ALDH1A1 (0.53) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL20512232 | 0.73 | ALDH1A1 (0.48) | USP2MEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL20512263 | 0.72 | KMT2A (0.56) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20512235 | 0.72 | CA1 (0.46) | CYP19A1MEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-12-13 | — | — | US | disclosed |
| US-10138252-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-11-27 | — | — | US | disclosed |
| US-20180305371-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-10-25 | — | — | US | disclosed |
| US-10087190-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | CYP19A1 1049/4885HKDC1 3198/4885USP2 3016/4885 |
| US-20180305371-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | CYP19A1 1049/4885HKDC1 3198/4885USP2 3016/4885 |
| US-10138252-B1 | Lactones | DHPS, FDPS, LSS | CYP19A1 850/4885HKDC1 3232/4885USP2 2830/4885 |
| US-10087190-B1 | Lactones | DHPS, FDPS, LSS | CYP19A1 850/4885HKDC1 3232/4885USP2 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.