Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | MMP10 | P09238 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20512253 | 0.87 | ALDH1A1 (0.51) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL20512258 | 0.85 | NPSR1 (0.51) | ALDH1A1MEN1KMT2ACYP19A1LMNA | |
| SCHEMBL20512263 | 0.82 | KMT2A (0.56) | CA1CA2MMP1ALDH1A1MEN1 | |
| SCHEMBL20512265 | 0.77 | ALDH1A1 (0.50) | CA2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20512228 | 0.77 | EGFR (0.45) | ALDH1A1MEN1KMT2ACYP19A1LMNA | |
| SCHEMBL20512232 | 0.74 | ALDH1A1 (0.48) | CA2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20512274 | 0.72 | CYP19A1 (0.43) | ALDH1A1MEN1KMT2ACYP19A1LMNA | |
| SCHEMBL20512270 | 0.71 | ALDH1A1 (0.55) | CA1CA2MMP1ALDH1A1MEN1 | |
| SCHEMBL20512230 | 0.71 | ALDH1A1 (0.54) | CA2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12003451 | 0.70 | FFAR1 (0.38) | ALDH1A1MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-12-13 | — | — | US | disclosed |
| US-10138252-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-11-27 | — | — | US | disclosed |
| US-20180305371-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-10-25 | — | — | US | disclosed |
| US-10087190-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | CA1 2993/4885CA2 3221/4885MMP7 4520/4885 |
| US-20180305371-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | CA1 2993/4885CA2 3221/4885MMP7 4520/4885 |
| US-10138252-B1 | Lactones | DHPS, FDPS, LSS | CA1 2829/4885CA2 2868/4885MMP7 4423/4885 |
| US-10087190-B1 | Lactones | DHPS, FDPS, LSS | CA1 2829/4885CA2 2868/4885MMP7 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.