Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 11/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606870 | 0.72 | TERT (0.46) | GAALMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7968937 | 0.67 | MAPT (0.64) | KMT2AGAAMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL5192592 | 0.67 | KMT2A (0.70) | KMT2AGAAMEN1LMNARAB9A | |
| SCHEMBL11142926 | 0.66 | TAS1R3 (0.67) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL18359200 | 0.65 | NPC1 (0.68) | KMT2AGAAMEN1LMNARAB9A | |
| 3,4-Methylendioxy Acetophenone SCHEMBL137979 | 0.65 | KDM4E (0.71) | KMT2AMEN1RAB9ASMN1; SMN2KDM4E | |
| 3,4-Methylendioxy Acetophenone SCHEMBL29405437 | 0.65 | KDM4E (0.71) | KMT2AMEN1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5010361 | 0.64 | TAS1R3 (0.61) | KMT2AGAAMEN1LMNARAB9A | |
| SCHEMBL108225 | 0.64 | ALDH1A1 (0.90) | KMT2AGAALMNAALDH1A1HPGD | |
| SCHEMBL21165315 | 0.64 | NPC1 (0.66) | KMT2AGAAMEN1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011066864-A1 | METHOD AND COMPOSITIONS FOR INHIBITION OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011066864-A1 | METHOD AND COMPOSITIONS FOR INHIBITION OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2011-06-09 | — | — | WO | disclosed |