Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29761334 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2ALMNAHPGDMEN1 | |
| SCHEMBL20522634 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2ALMNAHPGDMEN1 | |
| SCHEMBL20522637 | 0.86 | NPEPPS (0.37) | SMN1; SMN2KMT2ALMNAHPGDMEN1 | |
| SCHEMBL28627221 | 0.82 | HPGD (0.39) | SMN1; SMN2KMT2ALMNAHPGDMEN1 | |
| SCHEMBL20522632 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAHPGDALDH1A1KDM4E | |
| SCHEMBL25202984 | 0.80 | HPGD (0.38) | SMN1; SMN2KMT2AHPGDMEN1KDM4E | |
| SCHEMBL18797102 | 0.76 | COMT (0.36) | SMN1; SMN2KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL29058918 | 0.75 | MEN1 (0.34) | SMN1; SMN2KMT2ALMNAHPGDMEN1 | |
| SCHEMBL29058642 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2ALMNAHPGDMEN1 | |
| SCHEMBL31091769 | 0.72 | KAT2B (0.50) | SMN1; SMN2KMT2AHPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11292770-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2022-04-05 | — | — | US | claimed |
| EP-3601263-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-10-13 | — | — | EP | claimed |
| US-20200109123-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2020-04-09 | — | — | US | claimed |
| EP-3601263-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC Corporation (US) | 2020-02-05 | — | — | EP | claimed |
| WO-2018183432-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION (US) | 2018-10-04 | — | — | WO | claimed |
| EP-4267556-B1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2025-04-09 | — | — | EP | disclosed |
| US-20240101519-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2024-03-28 | — | — | US | disclosed |
| EP-4267556-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORATION (US) | 2023-11-01 | — | — | EP | disclosed |
| CN-116635386-A | Substituted pyridazinone herbicides | FMC公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022140309-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORTION (US) | 2022-06-30 | — | — | WO | disclosed |
| US-11292770-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2022-04-05 | — | — | US | disclosed |
| EP-3601263-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-10-13 | — | — | EP | disclosed |
| US-20200109123-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2020-04-09 | — | — | US | disclosed |
| EP-3601263-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC Corporation (US) | 2020-02-05 | — | — | EP | disclosed |
| CN-110741000-A | Novel pyridazinone herbicides | FMC公司 | 2020-01-31 | — | — | CN | disclosed |
| WO-2018183432-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION (US) | 2018-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101519-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | PRDX4, PRDX6, PDXK | SMN1; SMN2 3057/4885KMT2A 2994/4885LMNA 3586/4885 |
| US-11292770-B2 | Pyridazinone herbicides | PRDX6, PRDX4, PDXK | SMN1; SMN2 3789/4885KMT2A 2317/4885LMNA 1888/4885 |
| US-20200109123-A1 | NOVEL PYRIDAZINONE HERBICIDES | PRDX6, PRDX4, CHRM2 | SMN1; SMN2 3866/4885KMT2A 2431/4885LMNA 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.