Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL28609463 | 0.88 | ATM (0.36) | HPGDHSD11B1SMN1; SMN2MEN1MAPT | |
| SCHEMBL21835458 | 0.87 | HSD11B1 (0.38) | HPGDHSD11B1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29383185 | 0.87 | HSD11B1 (0.38) | HPGDHSD11B1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29443524 | 0.86 | MEN1 (0.33) | HPGDSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL21835397 | 0.86 | MEN1 (0.33) | HPGDSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL25184883 | 0.86 | MAPK8 (0.37) | HSD11B1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL20522637 | 0.85 | NPEPPS (0.37) | HPGDSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL30834467 | 0.84 | TSHR (0.38) | SMN1; SMN2KMT2AKDM4EL3MBTL1TSHR | |
| SCHEMBL21835495 | 0.82 | NPBWR1 (0.41) | HPGDHSD11B1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29382816 | 0.82 | NPBWR1 (0.41) | HPGDHSD11B1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435044-B2 | Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide | FMC CORPORATION (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250304990-A1 | HERBICIDE RESISTANCE | SYNGENTA CROP PROTECTION AG (CH) | 2025-10-02 | — | — | US | disclosed |
| CN-119039233-A | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118994028-A | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-113166075-B | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118265781-A | Herbicide resistance | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2023083972-A1 | HERBICIDE RESISTANCE | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-19 | — | — | WO | disclosed |
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
| US-20220041560-A1 | PYRIDAZINONE HERBICIDES AND PYRIDAZINONE INTERMEDIATES USED TO PREPARE A HERBICIDE | FMC CORPORATION | 2022-02-10 | — | — | US | disclosed |
| CN-113166075-A | Pyridazinone herbicides and pyridazinone intermediates for the preparation thereof | FMC公司 | 2021-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | CYP1B1, CHRM2, CYP1A1 | HPGD 390/4885HSD11B1 295/4885SMN1; SMN2 2651/4885 |
| US-12435044-B2 | Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide | CBR3, CBR1, CYP4F3 | HPGD 477/4885HSD11B1 959/4885SMN1; SMN2 4796/4885 |
| US-20220041560-A1 | PYRIDAZINONE HERBICIDES AND PYRIDAZINONE INTERMEDIATES USED TO PREPARE A HERBICIDE | CBR3, CBR1, CYP4F3 | HPGD 477/4885HSD11B1 959/4885SMN1; SMN2 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.