Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058636 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL29761324 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNATP53POLBMEN1 | |
| SCHEMBL20522632 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAALDH1A1KDM4EGAA | |
| SCHEMBL29058598 | 0.77 | LMNA (0.32) | SMN1; SMN2LMNATP53POLBALDH1A1 | |
| SCHEMBL29058623 | 0.75 | ALDH1A1 (0.37) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29761330 | 0.75 | ALDH1A1 (0.37) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29761332 | 0.75 | ALDH1A1 (0.37) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20522635 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAPOLBALDH1A1KDM4E | |
| SCHEMBL29761334 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAPOLBALDH1A1KDM4E | |
| SCHEMBL29761331 | 0.70 | MMP1 (0.34) | SMN1; SMN2LMNATP53POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267556-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORATION (US) | 2023-11-01 | — | — | EP | disclosed |
| CN-116635386-A | Substituted pyridazinone herbicides | FMC公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022140309-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORTION (US) | 2022-06-30 | — | — | WO | disclosed |