Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28149986 | 0.74 | HDAC1 (0.40) | SCN9AL3MBTL1SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL30961230 | 0.70 | SIGMAR1 (0.45) | SCN9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL20523411 | 0.64 | CNR2 (0.34) | SCN9ADRD3L3MBTL1SMN1; SMN2CNR2 | |
| SCHEMBL20523413 | 0.64 | L3MBTL1 (0.34) | SCN9AL3MBTL1SMN1; SMN2CNR2 | |
| SCHEMBL20523647 | 0.63 | CNR2 (0.33) | SCN9AL3MBTL1SMN1; SMN2CNR2 | |
| SCHEMBL22585602 | 0.63 | L3MBTL1 (0.48) | SCN9AL3MBTL1TRPV3 | |
| SCHEMBL11490207 | 0.62 | LMNA (0.35) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL22943261 | 0.62 | HDAC1 (0.36) | — | |
| SCHEMBL21627398 | 0.61 | SIGMAR1 (0.53) | SCN9A | |
| SCHEMBL23009960 | 0.60 | NFE2L2 (0.40) | PTGS2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600327-A1 | HETEROCYCLIC COMPOUND | Cardurion Pharmaceuticals, LLC (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183112-A1 | HETEROCYCLIC COMPOUND | CARDURION PHARMACEUTICALS, LLC (US) | 2018-10-04 | — | — | WO | disclosed |