Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525430 | 0.89 | PARP1 (0.41) | PARP1RPS6KB1AKT1 | |
| SCHEMBL20525448 | 0.89 | RPS6KB1 (0.41) | SMN1; SMN2KDM4EPARP1RPS6KB1ALDH1A1 | |
| SCHEMBL18108887 | 0.82 | MAPT (0.45) | SMN1; SMN2KDM4ELMNAHTTHPGD | |
| SCHEMBL20525450 | 0.81 | F12 (0.36) | PARP1RPS6KB1 | |
| SCHEMBL18108893 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4ELMNAHTTHPGD | |
| SCHEMBL20525447 | 0.80 | HTR6 (0.41) | KDM4EPARP1ALDH1A1 | |
| SCHEMBL20525410 | 0.79 | ENPP2 (0.36) | RPS6KB1JAK2AKT1 | |
| SCHEMBL20525423 | 0.79 | SCN9A (0.42) | KDM4EPARP1ALDH1A1 | |
| SCHEMBL20525353 | 0.77 | HDAC1 (0.41) | LMNAALDH1A1MAPT | |
| SCHEMBL20525344 | 0.75 | DRD2 (0.33) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080125-B1 | NOVEL AZAINDOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE (HDAC) INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-10-10 | — | — | EP | disclosed |