Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allethrin SCHEMBL7171209 | 0.94 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1MAPTALOX15 | |
| Chlorpyrifos SCHEMBL7174685 | 0.90 | TDP1 (0.44) | TDP1CYP3A4ALDH1A1MAPTALOX15 | |
| Chlorpyrifos-Methyl SCHEMBL7173269 | 0.83 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1MAPTALOX15 | |
| Allethrin SCHEMBL7175265 | 0.83 | TSHR (0.46) | TDP1CYP3A4ALDH1A1TSHRHSD17B10 | |
| Allethrin SCHEMBL10722528 | 0.81 | CYP3A4 (0.44) | TDP1CYP3A4ALDH1A1MAPTALOX15 | |
| Bioallethrin SCHEMBL9253613 | 0.80 | LMNA (0.46) | TDP1CYP3A4TSHRLMNACYP1A2 | |
| Bioallethrin SCHEMBL7174195 | 0.80 | LMNA (0.46) | TDP1CYP3A4TSHRLMNACYP1A2 | |
| Allethrin SCHEMBL26963 | 0.80 | LMNA (0.46) | TDP1CYP3A4TSHRLMNACYP1A2 | |
| Bioallethrin SCHEMBL411848 | 0.80 | LMNA (0.46) | TDP1CYP3A4TSHRLMNACYP1A2 | |
| Bioallethrin SCHEMBL8648414 | 0.80 | LMNA (0.46) | TDP1CYP3A4TSHRLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8901154-B2 | High concentration topical insecticides containing pyrethroids | CEVA ANIMAL HEALTH LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-20110144166-A1 | HIGH CONCENTRATION TOPICAL INSECTICIDES CONTAINING PYRETHROIDS | NATIXIS, AS SECURITY AGENT (FR) | 2011-06-16 | — | — | US | disclosed |
| US-7906535-B2 | High concentration topical insecticides containing pyrethroids | SUMMIT VETPHARM, LLC (US) | 2011-03-15 | — | — | US | disclosed |
| US-7345092-B2 | High concentration topical insecticides containing pyrethroids | SUMMIT VETPHARM, LLC (US) | 2008-03-18 | — | — | US | disclosed |
| US-20070276014-A1 | HIGH CONCENTRATION TOPICAL INSECTICIES CONTAINING PYRETHROIDS | NATIXIS, AS SECURITY AGENT (FR) | 2007-11-29 | — | — | US | disclosed |
| US-20050245582-A1 | First insecticide for killing fleas is permethrin or phenothrin; insect growth regulator is pyriproxyfen or methoprene; second insecticide for killing ticks is acetamiprid, triphenyl phosphate to incease effectiveness of acetamiprid | THE HARTZ MOUNTAIN CORPORATION | 2005-11-03 | — | — | US | disclosed |
| US-20050009881-A1 | High concentration topical insecticides containing pyrethroids | NATIXIS, AS SECURITY AGENT (FR) | 2005-01-13 | — | — | US | disclosed |
| EP-1322166-A2 | SEED TREATMENT WITH COMBINATIONS OF INSECTICIDES | Monsanto Technology LLP (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028186-A2 | SEED TREATMENT WITH COMBINATIONS OF INSECTICIDES | MONSANTO TECHNOLOGY, LLC (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245582-A1 | First insecticide for killing fleas is permethrin or phenothrin; insect growth regulator is pyriproxyfen or methoprene; second insecticide for killing ticks is acetamiprid, triphenyl phosphate to incease effectiveness of acetamiprid | IGF2BP3, TRHR, TRHDE | TDP1 2226/4885CYP3A4 2759/4885ALDH1A1 2833/4885 |
| US-20050009881-A1 | High concentration topical insecticides containing pyrethroids | GHRHR, IGFBP2, IGF1R | TDP1 3065/4885CYP3A4 1066/4885ALDH1A1 4288/4885 |
| US-20110144166-A1 | HIGH CONCENTRATION TOPICAL INSECTICIDES CONTAINING PYRETHROIDS | GHRHR, IGFBP2, IGF1R | TDP1 3065/4885CYP3A4 1066/4885ALDH1A1 4288/4885 |
| US-20070276014-A1 | HIGH CONCENTRATION TOPICAL INSECTICIES CONTAINING PYRETHROIDS | IGFBP2, GHRHR, IGF1R | TDP1 3209/4885CYP3A4 994/4885ALDH1A1 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.