Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | HRH1 | P35367 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201504 | 0.93 | FGFR1 (0.31) | — | |
| SCHEMBL2470883 | 0.90 | DRD2 (0.39) | DRD2DRD4HRH1DRD3HRH2 | |
| SCHEMBL2018673 | 0.90 | DRD2 (0.32) | DRD2DRD4HRH1DRD3HRH2 | |
| SCHEMBL1965737 | 0.89 | ADRA1A (0.35) | DRD2DRD4HRH1DRD3HRH2 | |
| SCHEMBL2200006 | 0.89 | ACHE (0.35) | DRD2HRH1MAPTTSHRADRA2B | |
| SCHEMBL2200403 | 0.89 | GAA (0.32) | GAAMAPTSMN1; SMN2 | |
| SCHEMBL2470994 | 0.88 | DRD2 (0.33) | DRD2DRD4HRH1DRD3HRH2 | |
| SCHEMBL2023151 | 0.87 | DRD2 (0.31) | DRD2DRD4HRH1DRD3HRH2 | |
| SCHEMBL1963472 | 0.87 | DRD2 (0.35) | DRD2DRD4HRH1DRD3HRH2 | |
| SCHEMBL11995963 | 0.87 | PIK3CA (0.35) | DRD2DRD4HRH1DRD3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999908-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-06-04 | — | — | US | claimed |
| US-11945895-B2 | Photochromic polydiorganosiloxane vinylic crosslinkers | ALCON INC. (CH) | 2024-04-02 | — | — | US | claimed |
| US-11833771-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2023-12-05 | — | — | US | claimed |
| US-20210284806-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC. (CH) | 2021-09-16 | — | — | US | claimed |
| US-20210284778-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC (CH) | 2021-09-16 | — | — | US | claimed |
| US-11945181-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-04-02 | — | — | US | disclosed |
| US-11945895-B2 | Photochromic polydiorganosiloxane vinylic crosslinkers | ALCON INC. (CH) | 2024-04-02 | — | — | US | disclosed |
| US-11833771-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2023-12-05 | — | — | US | disclosed |
| US-20220126541-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-04-28 | — | — | US | disclosed |
| US-20210284806-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC. (CH) | 2021-09-16 | — | — | US | disclosed |
| US-20210284778-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC (CH) | 2021-09-16 | — | — | US | disclosed |
| US-20180291009-A1 | Photochromic Compounds | TRANSITIONS OPTICAL, INC. | 2018-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180291009-A1 | Photochromic Compounds | CCR4, CCR8, CBR3 | DRD2 182/4885DRD4 91/4885HRH1 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.