Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25062005 | 0.85 | LMNA (0.58) | ALDH1A1MAPK1L3MBTL1LMNAGAA | |
| SCHEMBL13299628 | 0.82 | GAA (0.62) | EGFRALDH1A1MAPK1LMNAGAA | |
| SCHEMBL2069136 | 0.79 | ATM (0.48) | GLAEGFRERBB2ALDH1A1MAPK1 | |
| SCHEMBL3457564 | 0.78 | ATM (0.56) | EGFRERBB2ATMMMP2FFAR1 | |
| SCHEMBL20534589 | 0.78 | HDAC3 (0.43) | ALDH1A1MAPK1L3MBTL1LMNAGAA | |
| SCHEMBL1724245 | 0.77 | ALDH1A1 (0.69) | GLAEGFRERBB2ALDH1A1MAPK1 | |
| SCHEMBL27678845 | 0.76 | MMP2 (0.52) | EGFRERBB2MAOBMMP2KMT2A | |
| SCHEMBL28538179 | 0.76 | HSD11B1 (0.56) | ALDH1A1MAPK1L3MBTL1ATMKMT2A | |
| SCHEMBL30209492 | 0.76 | HSD11B1 (0.56) | ALDH1A1MAPK1L3MBTL1ATMKMT2A | |
| SCHEMBL24390160 | 0.75 | KMT2A (0.44) | ALDH1A1MAPK1L3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-16 | — | — | US | disclosed |
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-16 | — | — | US | disclosed |
| EP-3609880-A1 | LIVER X RECEPTORS (LXR) MODULATORS | Phenex-FXR GmbH (DE) | 2020-02-19 | — | — | EP | disclosed |
| CN-110546144-A | Liver X Receptor (LXR) modulators | PHENEX FXR GMBH | 2019-12-06 | — | — | CN | disclosed |
| WO-2018188795-A1 | LIVER X RECEPTORS (LXR) MODULATORS | PHENEX-FXR GMBH (DE) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | GLA 1779/4885EGFR 723/4885ERBB2 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.