SCHEMBL987485

SCHEMBL987485

CCO[Si](OCC)(OCC)c1cccc(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
ATM Q13315 1/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 5/20 0.34
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
NLRP3 Q96P20 1/20 0.34
KEAP1 Q14145 1/20 0.33
HTR1B P28222 1/20 0.33
NUDT1 P36639 1/20 0.33
CYP1A2 P05177 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 1/20 0.32
S1PR1 P21453 1/20 0.31
ELANE P08246 1/20 0.31
CYP2A6 P11509 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13027884 0.90 CYP1A2 (0.35) CYP1A2
SCHEMBL27523422 0.87 GAA (0.35) TRPA1ATMGAAMAPTALDH1A1
SCHEMBL29022755 0.85 HTR1B (0.35) TRPA1ATMGAAMAPTALDH1A1
SCHEMBL28236979 0.84 TRPA1 (0.35) TRPA1ATMGAAMAPTALDH1A1
SCHEMBL109759 0.83 TSHR (0.38) GAAMAPTALDH1A1CYP3A4CYP1A2
SCHEMBL13027881 0.82 CYP1A2 (0.35) CYP1A2ELANECYP2A6
SCHEMBL20535490 0.82 TRPA1 (0.34) TRPA1ATMGAAMAPTALDH1A1
SCHEMBL13027138 0.82
SCHEMBL728385 0.81 CYP1A2 (0.31) GAAMAPTCYP1A2KDM4E
SCHEMBL13027177 0.79 CA12 (0.37) GAAMAPTALDH1A1CYP3A4KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4488317-A1 METHOD FOR PRODUCING CURABLE RESIN COMPOSITION Kaneka Corporation (JP) 2025-01-08 EP disclosed
CN-118556096-A Method for producing curable resin composition 株式会社钟化 2024-08-27 CN disclosed
EP-4410871-A1 POLYMER AND CURABLE COMPOSITION Kaneka Corporation (JP) 2024-08-07 EP disclosed
WO-2023162782-A1 METHOD FOR PRODUCING CURABLE RESIN COMPOSITION 株式会社カネカ 2023-08-31 WO disclosed
CN-108473684-B Process for producing siloxane polymer 东丽精细化工株式会社 2023-05-12 CN disclosed
WO-2023053988-A1 POLYMER AND CURABLE COMPOSITION 株式会社カネカ 2023-04-06 WO disclosed
US-10647821-B2 Production process for silicone polymer TORAY FINE CHEMICALS CO., LTD. (JP) 2020-05-12 US disclosed
US-20190023848-A1 PRODUCTION PROCESS FOR SILICONE POLYMER TORAY FINE CHEMICALS CO., LTD. (JP) 2019-01-24 US disclosed
EP-2275427-B1 Ruthenium-diamine complex and methods for producing optically active compounds TAKASAGO PERFUMERY CO LTD (JP) 2013-09-11 EP disclosed
US-8404879-B2 Ruthenium-diamine complex and methods for producing optically active compounds TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-03-26 US disclosed
EP-2275427-A1 Ruthenium-diamine complex and methods for producing optically active compounds Takasago International Corporation (JP) 2011-01-19 EP disclosed
US-20110009646-A1 RUTHENIUM-DIAMINE COMPLEX AND METHODS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-01-13 US disclosed
EP-0985510-B1 ARTICLE WITH UNEVEN SURFACE, PROCESS FOR PRODUCING THE SAME, AND COMPOSITION THEREFOR NIPPON SHEET GLASS CO LTD (JP) 2003-09-24 EP disclosed
US-20020064666-A1 Article having uneven surface, production process for the article, and composition for the process SHINMO KATSUHIDE (JP) 2002-05-30 US disclosed
US-6361718-B1 MOLDING POLYSILOXANE FILMS FROM SILANOLS AND SILANE HALIDES; HEAT RESISTANT AND NONCRACKING; USED TO MANUFACTURE OPTICAL RECORDING MEDIA NIPPON SHEET GLASS CO., LTD. (JP) 2002-03-26 US disclosed
EP-1142682-A1 METHOD FOR PRODUCING ARTICLE HAVING PREDETERMINED SURFACE SHAPE, AND OPTICAL WAVEGUIDE ELEMENT Nippon Sheet Glass Co., Ltd. (JP) 2001-10-10 EP disclosed
EP-0985510-A1 ARTICLE WITH ROUGH SURFACE, PROCESS FOR PRODUCING THE SAME, AND COMPOSITION THEREFOR Nippon Sheet Glass Co., Ltd. (JP) 2000-03-15 EP disclosed
EP-0258788-B1 PROCESS FOR PREPARING PROPYLENE HOMO- AND COPOLYMERS BY MEANS OF A ZIEGLER-NATTA CATALYTIC SYSTEM BASF Aktiengesellschaft (DE) 1990-05-30 EP disclosed
EP-0258788-A1 Process for preparing propylene homo- and copolymers by means of a Ziegler-Natta catalytic system BASF Aktiengesellschaft (DE) 1988-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009646-A1 RUTHENIUM-DIAMINE COMPLEX AND METHODS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS ADH5, AOC1, ADH1A TRPA1 1431/4885ATM 2758/4885GAA 2425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.