Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051292 | 0.85 | ACSS2 (0.40) | PPARGMAPTRAB9ANLRP3ACSS2 | |
| SCHEMBL2016915 | 0.77 | MAPT (0.46) | PPARGNPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL2017964 | 0.76 | SCNN1A (0.44) | PPARGNPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL2015354 | 0.74 | PPARG (0.52) | PPARGNPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL2018222 | 0.74 | MAPT (0.51) | PPARGNPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL2017353 | 0.71 | MAPT (0.52) | PPARGNPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL12635707 | 0.71 | PPARG (0.45) | PPARGDYRK1ANPC1MAPTCYP1A2 | |
| SCHEMBL12635938 | 0.70 | MAPT (0.46) | NPC1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2014103 | 0.70 | SCNN1A (0.43) | PPARGNPC1MAPTNLRP3ALDH1A1 | |
| SCHEMBL2018438 | 0.69 | SCNN1A (0.44) | MAPTACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |