Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 18/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391960 | 0.85 | MTNR1A (0.50) | UTS2R | |
| SCHEMBL20544740 | 0.82 | ROCK2 (0.47) | UTS2R | |
| SCHEMBL20544982 | 0.82 | WDR91 (0.49) | UTS2R | |
| SCHEMBL20544753 | 0.82 | THRB (0.48) | UTS2R | |
| SCHEMBL22278104 | 0.81 | UTS2R (0.45) | UTS2RSLC6A4 | |
| SCHEMBL20544752 | 0.81 | UTS2R (0.48) | UTS2R | |
| SCHEMBL391098 | 0.80 | P2RY2 (0.47) | UTS2R | |
| SCHEMBL20544940 | 0.80 | UTS2R (0.51) | UTS2R | |
| SCHEMBL20544776 | 0.80 | UTS2R (0.73) | UTS2R | |
| SCHEMBL20544741 | 0.79 | UTS2R (0.51) | UTS2RCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180312516-A1 | Protein Kinase B Inhibitors | ASTRAZENECA AB (SE) | 2018-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312516-A1 | Protein Kinase B Inhibitors | PRKAR2B, PRKCB, AKT1 | UTS2R 3101/4885CYP26A1 4656/4885SLC6A4 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.