SCHEMBL20544940

SCHEMBL20544940

COCCC(NC(=O)O)c1ccc(Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1953141 0.86 TAS1R3 (0.51) UTS2R
SCHEMBL392486 0.82 UTS2R (0.46) UTS2R
SCHEMBL20544982 0.81 WDR91 (0.49) UTS2R
SCHEMBL2104560 0.80 ACHE (0.48)
SCHEMBL20544787 0.80 UTS2R (0.49) UTS2R
SCHEMBL20544752 0.80 UTS2R (0.48) UTS2R
SCHEMBL20544776 0.79 UTS2R (0.73) UTS2R
SCHEMBL20544741 0.78 UTS2R (0.51) UTS2R
SCHEMBL391960 0.78 MTNR1A (0.50) UTS2R
SCHEMBL21979535 0.77 KDM4E (0.47) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180312516-A1 Protein Kinase B Inhibitors ASTRAZENECA AB (SE) 2018-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180312516-A1 Protein Kinase B Inhibitors PRKAR2B, PRKCB, AKT1 UTS2R 3101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.