Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | LPL | P06858 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19099723 | 0.88 | SIGMAR1 (0.43) | SIGMAR1OPRM1ALDH1A1TSHRLMNA | |
| SCHEMBL3663957 | 0.83 | LPL (0.43) | SIGMAR1OPRM1LPLLIPGALDH1A1 | |
| SCHEMBL1089165 | 0.81 | SIGMAR1 (0.61) | SIGMAR1OPRM1LMNAPOLBMEN1 | |
| SCHEMBL27934011 | 0.75 | ALDH1A1 (0.62) | SIGMAR1LPLLIPGALDH1A1TSHR | |
| SCHEMBL2320439 | 0.75 | LMNA (0.61) | LPLLIPGALDH1A1LMNAHRH3 | |
| SCHEMBL28440571 | 0.74 | LMNA (0.53) | ALDH1A1LMNAHRH3 | |
| SCHEMBL20548515 | 0.74 | LPL (0.42) | SIGMAR1OPRM1LPLLIPGSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21747953 | 0.73 | LMNA (0.59) | LPLLIPGALDH1A1LMNAHRH3 | |
| SCHEMBL2557827 | 0.72 | HRH3 (0.65) | ALDH1A1POLBSMN1; SMN2HRH3 | |
| SCHEMBL29951850 | 0.72 | LPL (0.50) | SIGMAR1LPLLIPGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398598-B1 | SULFONAMIDE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | HITGEN INC (CN) | 2022-04-06 | — | — | EP | disclosed |
| EP-3398598-A1 | SULFONAMIDE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | Hitgen Ltd. (CN) | 2018-11-07 | — | — | EP | disclosed |