Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | CHKA | P35790 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320439 | 0.92 | LMNA (0.61) | LMNAMC4RCHKAALDH1A1HDAC6 | |
| Hydrochloric Acid SCHEMBL21747953 | 0.91 | LMNA (0.59) | LMNAMC4RCHKAALDH1A1HDAC6 | |
| SCHEMBL16121611 | 0.86 | CHKA (0.69) | LMNAMC4RCHKAKDM4ECA2 | |
| SCHEMBL29113925 | 0.84 | HRH3 (0.54) | LMNAALDH1A1MAPTHRH3HPGD | |
| SCHEMBL17165356 | 0.83 | MC4R (0.50) | LMNAMC4RCHKAALDH1A1HDAC6 | |
| SCHEMBL14934864 | 0.82 | HRH3 (0.53) | LMNAMC4RCHKAALDH1A1HDAC6 | |
| SCHEMBL3584969 | 0.82 | ALDH1A1 (0.47) | LMNAMC4RCHKAALDH1A1HDAC6 | |
| SCHEMBL3716741 | 0.81 | LMNA (0.47) | LMNAMC4RCHKAALDH1A1HDAC6 | |
| SCHEMBL3663957 | 0.81 | LPL (0.43) | LMNAMC4RCHKAALDH1A1CA2 | |
| SCHEMBL29951850 | 0.80 | LPL (0.50) | LMNAMC4RCHKAALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126036-A | 7-Azaindole compound and preparation method and application thereof | 复旦大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-117447470-A | Pyrrolopyridine derivative as HPK1 inhibitor, preparation method and application thereof | 杭州医学院 | 2024-01-26 | — | — | CN | disclosed |
| CN-117050072-A | Pyrazolopyridine derivative and application thereof | 沈阳药科大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-106928198-B | Sulfonamide derivative and preparation method and application thereof | 成都先导药物开发股份有限公司 | 2020-07-28 | — | — | CN | disclosed |