Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934011 | 0.86 | ALDH1A1 (0.62) | LPLLIPGALDH1A1CA1CA2 | |
| SCHEMBL2320439 | 0.86 | LMNA (0.61) | LPLLIPGALDH1A1CA2NPC1 | |
| SCHEMBL21550770 | 0.85 | PKM (0.54) | LPLLIPGALDH1A1SIGMAR1NPC1 | |
| Hydrochloric Acid SCHEMBL21747953 | 0.85 | LMNA (0.59) | LPLLIPGALDH1A1CA2NPC1 | |
| SCHEMBL29955859 | 0.81 | LPL (0.51) | LPLLIPGALDH1A1SIGMAR1LMNA | |
| SCHEMBL16121611 | 0.81 | CHKA (0.69) | CA2LMNAMC4RCHKAHRH3 | |
| SCHEMBL2557827 | 0.80 | HRH3 (0.65) | ALDH1A1MBTD1L3MBTL3L3MBTL1POLB | |
| SCHEMBL2558087 | 0.80 | DRD2 (0.62) | SIGMAR1GAA | |
| SCHEMBL28440571 | 0.80 | LMNA (0.53) | ALDH1A1CA2NPC1TP53RAB9A | |
| SCHEMBL1427526 | 0.79 | HRH3 (0.69) | ALDH1A1MEN1KMT2AMBTD1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |