Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT7 | Q11130 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20549912 | 1.00 | FUT7 (0.41) | FUT7PPARAPPARGPSEN1PSEN2 | |
| SCHEMBL20550029 | 1.00 | FUT7 (0.41) | FUT7PPARAPPARGPSEN1PSEN2 | |
| SCHEMBL20767981 | 0.95 | CA2 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27641648 | 0.81 | CA2 (0.53) | FUT7PPARAPPARGPSEN1PSEN2 | |
| SCHEMBL30807989 | 0.78 | PTGS2 (0.48) | PPARATRPV1 | |
| SCHEMBL3169891 | 0.78 | PTGS2 (0.48) | PPARATRPV1 | |
| SCHEMBL3621448 | 0.76 | CA2 (0.54) | CA2TRPV1CA1CA9 | |
| SCHEMBL22345133 | 0.76 | RORA (0.48) | RORARORCRORB | |
| SCHEMBL28303636 | 0.76 | RORA (0.48) | RORARORCRORB | |
| SCHEMBL18091427 | 0.76 | ESR1 (0.46) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221153-B2 | Dibenzothiophene compounds | SAINT LOUIS UNIVERSITY (US) | 2019-03-05 | — | — | US | disclosed |
| US-20180319765-A1 | DIBENZOTHIOPHENE COMPOUNDS | SAINT LOUIS UNIVERSITY (US) | 2018-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221153-B2 | Dibenzothiophene compounds | DDT, TST, MPST | FUT7 4316/4885PPARA 1712/4885PPARG 2269/4885 |
| US-20180319765-A1 | DIBENZOTHIOPHENE COMPOUNDS | DDT, TST, MPST | FUT7 4316/4885PPARA 1712/4885PPARG 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.