Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2055294 | 0.96 | LCK (0.55) | LCKCHRM2NFKB1 | |
| SCHEMBL17123446 | 0.91 | LCK (0.52) | LCKCHRM2NFKB1 | |
| SCHEMBL23549865 | 0.90 | LCK (0.50) | LCKCHRM2NFKB1 | |
| SCHEMBL15929964 | 0.90 | LCK (0.50) | LCKCHRM2NFKB1 | |
| SCHEMBL817857 | 0.90 | LCK (0.50) | LCKCHRM2NFKB1 | |
| SCHEMBL19655070 | 0.90 | LCK (0.50) | LCKCHRM2NFKB1 | |
| SCHEMBL14790716 | 0.90 | LCK (0.50) | LCKCHRM2NFKB1 | |
| SCHEMBL3183226 | 0.89 | LCK (0.62) | LCKCHRM2NFKB1 | |
| SCHEMBL17332054 | 0.89 | LCK (0.46) | LCK | |
| SCHEMBL21229789 | 0.89 | LCK (0.46) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889738-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889738-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140219951-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140219951-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |
| US-20130266533-A1 | SULFONE POLYMER COMPOSITIONS | GENZYME CORPORATION | 2013-10-10 | — | — | US | disclosed |
| US-20130266533-A1 | SULFONE POLYMER COMPOSITIONS | GENZYME CORPORATION | 2013-10-10 | — | — | US | disclosed |
| US-20120237470-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120237470-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120196989-A1 | SYNTHESIS OF HOMOPOLYMERS AND BLOCK COPOLYMERS | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2012-08-02 | — | — | US | disclosed |
| US-8163799-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2012-04-24 | — | — | US | disclosed |
| US-20100196305-A1 | SULFONE POLYMER COMPOSITIONS | GENZYME CORPORATION | 2010-08-05 | — | — | US | disclosed |
| US-20100166696-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION | 2010-07-01 | — | — | US | disclosed |
| US-20100166696-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION | 2010-07-01 | — | — | US | disclosed |
| US-20100129309-A1 | AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION | 2010-05-27 | — | — | US | disclosed |
| US-20100129309-A1 | AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION | 2010-05-27 | — | — | US | disclosed |
| US-20100093857-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2010-04-15 | — | — | US | disclosed |
| US-20100093857-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2010-04-15 | — | — | US | disclosed |
| WO-2008133954-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008109095-A1 | SULFONE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008076242-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093857-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | PHPT1, PAM, PTH1R | LCK 3152/4885CHRM2 1714/4885NFKB1 4361/4885 |
| US-20100196305-A1 | SULFONE POLYMER COMPOSITIONS | SELE, MPST, PHOSPHO1 | LCK 687/4885CHRM2 2931/4885NFKB1 4477/4885 |
| US-20120237470-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | PHPT1, PAM, PTH1R | LCK 3152/4885CHRM2 1714/4885NFKB1 4361/4885 |
| US-20100166696-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | PAM, PHOSPHO1, ARID2 | LCK 3944/4885CHRM2 2449/4885NFKB1 3749/4885 |
| US-20100129309-A1 | AMINE POLYMER COMPOSITIONS | PHPT1, PHOSPHO1, PTH1R | LCK 1488/4885CHRM2 197/4885NFKB1 3995/4885 |
| US-20140219951-A1 | AMIDO-AMINE DENDRIMER COMPOSITIONS | PAM, ARGLU1, NAAA | LCK 4132/4885CHRM2 2415/4885NFKB1 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.