SCHEMBL2055294

SCHEMBL2055294

NCCN(CCN)CCCCN(CCN)CCN

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.55
CHRM2 P08172 1/20 0.38
NFKB1 P19838 1/20 0.33
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA3 P07451 2/20 0.31
CA4 P22748 2/20 0.31
CA6 P23280 2/20 0.31
CA5A P35218 2/20 0.31
CA7 P43166 2/20 0.31
CA9 Q16790 2/20 0.31
CA14 Q9ULX7 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
DNM1 Q05193 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2055293 0.96 LCK (0.52) LCKCHRM2NFKB1
SCHEMBL817857 0.93 LCK (0.50) LCKCHRM2NFKB1CA12CA1
SCHEMBL15929964 0.93 LCK (0.50) LCKCHRM2NFKB1CA12CA1
SCHEMBL19655070 0.93 LCK (0.50) LCKCHRM2NFKB1CA12CA1
SCHEMBL23549865 0.93 LCK (0.50) LCKCHRM2NFKB1CA12CA1
SCHEMBL3183226 0.92 LCK (0.62) LCKCHRM2NFKB1CA12CA1
SCHEMBL817594 0.90 CHRM2 (0.52) LCKCHRM2NFKB1CA12CA1
SCHEMBL10972803 0.90 LCK (0.48) LCKCHRM2NFKB1CA12CA1
SCHEMBL43276 0.89 LCK (0.52) LCKCHRM2NFKB1CA12CA1
SCHEMBL7166448 0.89 LCK (0.52) LCKCHRM2NFKB1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149894-A1 SORBENT MATERIAL FOR REMOVING CONTAMINANTS FROM WATER PURAFFINITY LTD (GB) 2023-05-18 US disclosed
EP-2511266-B1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES UNIV CALIFORNIA (US) 2019-09-04 EP disclosed
US-9556122-B2 Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-01-31 US disclosed
EP-2044090-B1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES UNIV CALIFORNIA (US) 2015-04-08 EP disclosed
US-8889738-B2 Amido-amine polymer compositions GENZYME CORPORATION (US) 2014-11-18 US disclosed
US-8889738-B2 Amido-amine polymer compositions GENZYME CORPORATION (US) 2014-11-18 US disclosed
US-20140219951-A1 AMIDO-AMINE DENDRIMER COMPOSITIONS GENZYME CORPORATION (US) 2014-08-07 US disclosed
US-20140219951-A1 AMIDO-AMINE DENDRIMER COMPOSITIONS GENZYME CORPORATION (US) 2014-08-07 US disclosed
US-20140039169-A1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2014-02-06 US disclosed
US-8557601-B2 Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-10-15 US disclosed
WO-2009154747-A1 PHARMACEUTICAL COMPOSITIONS GENZYME CORPORATION (US) 2009-12-23 WO disclosed
EP-2044090-A2 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-08 EP disclosed
WO-2008133954-A1 AMIDO-AMINE DENDRIMER COMPOSITIONS GENZYME CORPORATION (US) 2008-11-06 WO disclosed
WO-2008109095-A1 SULFONE POLYMER COMPOSITIONS GENZYME CORPORATION (US) 2008-09-12 WO disclosed
WO-2008103368-A1 AMINE POLYMER COMPOSITIONS GENZYME CORPORATION (US) 2008-08-28 WO disclosed
WO-2008076242-A1 AMIDO-AMINE POLYMER COMPOSITIONS GENZYME CORPORATION (US) 2008-06-26 WO disclosed
WO-2008008797-A2 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-01-17 WO disclosed
EP-0840727-B1 3-HYDROXY-2(1H)-PYRIDINONE CHELATING AGENTS UNIV CALIFORNIA (US) 2004-05-06 EP disclosed
US-5892029-A HIGHLY EFFECTIVE UPON BOTH INJECTION AND ORAL ADMINISTRATION. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-04-06 US disclosed
US-5624901-A CARBAMOYL SUBSTITUTED COMPOUNDS FOR CHELATE COMPOUNDS FOR MAGNETIC RESONANCE IMAGING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140039169-A1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES PLPBP, HPD, LASP1 LCK 982/4885CHRM2 3917/4885NFKB1 1653/4885
US-20140219951-A1 AMIDO-AMINE DENDRIMER COMPOSITIONS PAM, ARGLU1, NAAA LCK 4132/4885CHRM2 2415/4885NFKB1 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.