SCHEMBL205635

SCHEMBL205635

COC(=O)c1cc(Br)ccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.67
CA1 P00915 3/20 0.67
CA2 P00918 3/20 0.67
CA7 P43166 3/20 0.67
CA9 Q16790 3/20 0.67
CA14 Q9ULX7 3/20 0.67
HPGD P15428 2/20 0.62
CES2 O00748 1/20 0.62
GALR3 O60755 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2C9 P11712 1/20 0.62
ALOX15 P16050 1/20 0.62
CASP1 P29466 1/20 0.62
CYP2C19 P33261 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.59
LMNA P02545 2/20 0.55
TSHR P16473 1/20 0.55
PTGS2 P35354 1/20 0.54
GSTA1 P08263 1/20 0.53
GAA P10253 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30362168 1.00 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL29784278 0.86 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL12311622 0.85 HPGD (0.58) CA12CA1CA2CA7CA9
SCHEMBL1378325 0.85 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL29773857 0.84 NR4A2 (0.56) CA12CA1CA2CA7CA9
SCHEMBL4577829 0.84 NR4A2 (0.56) CA12CA1CA2CA7CA9
SCHEMBL2892460 0.83 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL861495 0.82 PTPN2 (0.54) CA12CA1CA2CA7CA9
SCHEMBL2482051 0.82 NR4A2 (0.54) CA12CA1CA2CA7CA9
SCHEMBL25028 0.81 HPGD (0.58) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 621 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978697-A Preparation method of high-temperature-resistant ABS material 惠州市聚创新材料科技有限公司 2025-05-13 CN claimed
CN-110713676-A Preparation process of wear-resistant power tube based on PVC material 安徽瑞琦塑胶科技有限公司 2020-01-21 CN claimed
US-20260132132-A1 3A,4,5,6-TETRAHYDRO-1 H-PYRAZOLO[3,4-C]PYRIDIN-7(7AH)-ONE DERIVATIVES AS FACTOR XIIA INHIBITORS KALVISTA PHARMACEUTICALS LTD (GB) 2026-05-14 US disclosed
CN-122010913-A Rhodamine-marked isoquinoline derivative and preparation method and application thereof 淮阴师范学院 2026-05-12 CN disclosed
US-12595239-B2 Substituted isoxazoline derivatives BASF SE (DE) 2026-04-07 US disclosed
US-20260085064-A1 SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF KARYOPHARM THERAPEUTICS INC (US) 2026-03-26 US disclosed
US-20260008770-A1 CBL-B INHIBITORS AND METHODS OF USES THEREOF INSILICO MEDICINE IP LTD (HK) 2026-01-08 US disclosed
US-20250340521-A1 C-ABL TYROSINE KINASE INHIBITORY COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2025-11-06 US disclosed
US-12435047-B2 c-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-10-07 US disclosed
US-20250268903-A1 RXFP1 AGONISTS BRISTOL MYERS SQUIBB CO (US) 2025-08-28 US disclosed
US-12398097-B2 WDR5-MYC inhibitors VANDERBILT UNIVERSITY (US) 2025-08-26 US disclosed
US-4634768-A INTERMEDIATES FOR VASODILATORS YAMAMOTO CHEMICAL INDUSTRIAL CO., LTD. (JP) 1987-01-06 US disclosed
US-4570006-A ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS TORII & CO. LTD. (JP) 1986-02-11 US disclosed
EP-0105484-B1 3-PROPIONYLSALICYCLIC ACID DERIVATIVES AND PROCESS FOR THE PREPARATION OF THE SAME Yamamoto Chemical Industrial Company, Limited (JP) 1986-01-15 EP disclosed
US-4533732-A CHEMICAL INTERMEDIATES TO PRODUCTION OF FLAVONES YAMAMOTO CHEMICAL INDUSTRIAL COMPANY, LIMITED (JP) 1985-08-06 US disclosed
US-4514416-A Amidine compound, process for producing same and anti-complement agent comprising same TORII & CO. LTD. (JP) 1985-04-30 US disclosed
EP-0107804-A1 3-Methylflavone-8-carboxylic acid derivatives and process for the preparation of the same Yamamoto Chemical Industrial Company, Limited (JP) 1984-05-09 EP disclosed
EP-0105484-A2 3-Propionylsalicyclic acid derivatives and process for the preparation of the same Yamamoto Chemical Industrial Company, Limited (JP) 1984-04-18 EP disclosed
US-4420476-A Benzofuro[3,2-c]pyrazol-3-amine derivatives Averst McKenna & Harrison, Inc. (CA) 1983-12-13 US disclosed
US-3993852-A DIALKYL PHENYLALKANEPHOSPHONATES CIBA-GEIGY AG (CH) 1976-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132132-A1 3A,4,5,6-TETRAHYDRO-1 H-PYRAZOLO[3,4-C]PYRIDIN-7(7AH)-ONE DERIVATIVES AS FACTOR XIIA INHIBITORS F11, F13B, F7 CA12 2665/4885CA1 2410/4885CA2 1177/4885
US-12435047-B2 c-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same ABL1, ABL2, MUSK CA12 3929/4885CA1 2508/4885CA2 1670/4885
US-12595239-B2 Substituted isoxazoline derivatives CBR3, ADRA2C, CYP4Z1 CA12 2451/4885CA1 2085/4885CA2 1520/4885
US-20260008770-A1 CBL-B INHIBITORS AND METHODS OF USES THEREOF CBL, CBLC, CBLB CA12 4302/4885CA1 3836/4885CA2 2201/4885
US-20250268903-A1 RXFP1 AGONISTS RXFP1, RXFP2, RXFP3 CA12 4434/4885CA1 4736/4885CA2 3556/4885
US-20250340521-A1 C-ABL TYROSINE KINASE INHIBITORY COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME ABL1, ABL2, MUSK CA12 3929/4885CA1 2508/4885CA2 1670/4885
US-12398097-B2 WDR5-MYC inhibitors MYC, WDR5, MYCBP CA12 4808/4885CA1 4853/4885CA2 4637/4885
US-20260085064-A1 SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF BCL6, MALT1, BCL6B CA12 964/4885CA1 1157/4885CA2 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.