Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2056736 | 0.87 | GPR35 (0.50) | GPR35TSHRCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL3500607 | 0.85 | GPR35 (0.57) | GPR35TSHRCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL29262876 | 0.82 | GPR35 (0.63) | GPR35CYP1A2ALDH1A1ALOX15RECQL | |
| SCHEMBL2100657 | 0.81 | TSHR (0.55) | GPR35TSHRCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL10981846 | 0.81 | TSHR (0.55) | GPR35TSHRCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL1828689 | 0.78 | TSHR (0.48) | TSHRCYP1A2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL11095264 | 0.78 | ALOX15 (0.58) | GPR35TSHRCYP1A2ALDH1A1CYP3A4 | |
| Nitric Acid SCHEMBL11648056 | 0.78 | TSHR (0.44) | GPR35TSHRCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL9500870 | 0.77 | GPR35 (0.68) | GPR35CYP1A2ALDH1A1ALOX15RECQL | |
| SCHEMBL314000 | 0.77 | TSHR (0.61) | GPR35TSHRCYP1A2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110052537-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY | 2011-03-03 | — | — | US | disclosed |
| WO-2009026184-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052537-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | TET1, ALKBH1, NQO1 | GPR35 2123/4885TSHR 3365/4885CYP1A2 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.