Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20675826 | 0.87 | ALDH1A1 (0.49) | GPR35ALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL2056822 | 0.87 | GPR35 (0.52) | GPR35ALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL18874784 | 0.82 | GPR35 (0.55) | GPR35ALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL11749237 | 0.79 | ALDH1A1 (0.49) | GPR35ALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL5586659 | 0.79 | GPR35 (0.55) | GPR35ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL11095264 | 0.77 | ALOX15 (0.58) | GPR35ALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL29262876 | 0.76 | GPR35 (0.63) | GPR35ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL10981846 | 0.76 | TSHR (0.55) | GPR35ALDH1A1CYP3A4ALOX15L3MBTL1 | |
| SCHEMBL21143325 | 0.76 | GPR35 (0.52) | GPR35ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL11095256 | 0.76 | GPR35 (0.62) | GPR35ALDH1A1CYP3A4ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110052537-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY | 2011-03-03 | — | — | US | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009026184-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052537-A1 | NITRO-BASED EXPLOSIVE REMEDIATION | TET1, ALKBH1, NQO1 | GPR35 2123/4885ALDH1A1 127/4885CYP3A4 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.