Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737266 | 0.84 | RBP4 (0.48) | PLA2G4AKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20570094 | 0.77 | CYP19A1 (0.44) | KDM5BIGF1RALOX15 | |
| SCHEMBL20569330 | 0.77 | HMOX1 (0.40) | KDM5BHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL20570736 | 0.75 | IGF1R (0.38) | TBXAS1KDM5BIGF1RALOX15 | |
| SCHEMBL2283649 | 0.74 | PLA2G4A (0.50) | PLA2G4AKDM5AKDM5BALOX15 | |
| SCHEMBL20569285 | 0.74 | L3MBTL1 (0.57) | — | |
| SCHEMBL30268827 | 0.73 | PLA2G4A (0.52) | PLA2G4ATBXAS1KDM5AKDM5BALOX15 | |
| SCHEMBL7265607 | 0.72 | PLA2G4A (0.39) | PLA2G4AKDM4CKDM5AKDM5B | |
| SCHEMBL27781577 | 0.72 | PLA2G4A (0.54) | PLA2G4ATBXAS1KDM5AKDM5BALOX15 | |
| SCHEMBL27781551 | 0.72 | PLA2G4A (0.54) | PLA2G4ATBXAS1KDM5AKDM5BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |