SCHEMBL20570495

SCHEMBL20570495

CCCCCCCCCCCC(=O)OCC=O

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.70
DGKA P23743 2/20 0.64
PAM P19021 2/20 0.58
MAPT P10636 2/20 0.55
LMNA P02545 4/20 0.53
DNM1 Q05193 1/20 0.53
ALDH1A1 P00352 1/20 0.53
KDM4E B2RXH2 1/20 0.51
DUSP3 P51452 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
PRKCA P17252 1/20 0.49
PRKCE Q02156 1/20 0.49
PRKCQ Q04759 1/20 0.49
PRKCD Q05655 1/20 0.49
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22126641 1.00 TSHR (0.70) TSHRDGKAPAMMAPTLMNA
SCHEMBL22126648 1.00 TSHR (0.70) TSHRDGKAPAMMAPTLMNA
SCHEMBL5668563 1.00 TSHR (0.70) TSHRDGKAPAMMAPTLMNA
SCHEMBL22126642 1.00 TSHR (0.70) TSHRDGKAPAMMAPTLMNA
SCHEMBL22126638 1.00 TSHR (0.70) TSHRDGKAPAMMAPTLMNA
SCHEMBL10411 1.00 TSHR (0.70) TSHRDGKAPAMMAPTLMNA
SCHEMBL5666555 0.98 TSHR (0.67) TSHRDGKAPAMMAPTLMNA
SCHEMBL250417 0.92 TSHR (0.58) TSHRDGKAPAMMAPTLMNA
SCHEMBL18036999 0.91 DGKA (0.60) TSHRDGKAMAPTLMNADUSP3
SCHEMBL11507812 0.87 TSHR (0.50) TSHRDGKAPAMMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630154-B1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF INSMED INC (US) 2026-05-13 EP disclosed
US-11857597-B2 Lipo-glycopeptide cleavable derivatives and uses thereof INSMED INCORPORATED (US) 2024-01-02 US disclosed
US-20220133843-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF BIOPHARMA CREDIT PLC (GB) 2022-05-05 US disclosed
US-11274073-B2 TRPV1 modulator compounds ANTALGENICS, S.L. (ES) 2022-03-15 US disclosed
US-20220024980-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF BIOPHARMA CREDIT PLC (GB) 2022-01-27 US disclosed
EP-3883589-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF Insmed Incorporated (US) 2021-09-29 EP disclosed
US-11071769-B2 Lipo-glycopeptide cleavable derivatives and uses thereof INSMED INCORPORATED (US) 2021-07-27 US disclosed
US-20200199063-A1 TRPV1 Modulator Compounds ANTALGENICS, S.L. (ES) 2020-06-25 US disclosed
US-20200155640-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF INSMED INCORPORATED (US) 2020-05-21 US disclosed
CN-110996984-A Lipoglycopeptide cleavable derivatives and uses thereof 英斯麦德公司 2020-04-10 CN disclosed
EP-3630154-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF Insmed Incorporated (US) 2020-04-08 EP disclosed
WO-2018217808-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF INSMED INCORPORATED (US) 2018-11-29 WO disclosed
CN-107261870-A Polyimide composition and method for producing separation membrane 财团法人纺织产业综合研究所 2017-10-20 CN disclosed
CN-106221462-A A kind of novel anti-aging glass cement 青岛燕园海洋生物科技有限公司 2016-12-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200155640-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF LGALS3BP, LGMN, LNPEP TSHR 3830/4885DGKA 1155/4885PAM 269/4885
US-11071769-B2 Lipo-glycopeptide cleavable derivatives and uses thereof LGALS3BP, LGMN, LNPEP TSHR 3830/4885DGKA 1155/4885PAM 269/4885
US-20220133843-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF LGALS3BP, LGMN, LNPEP TSHR 3830/4885DGKA 1155/4885PAM 269/4885
US-11274073-B2 TRPV1 modulator compounds TRPV1, TRPA1, TRPV3 TSHR 530/4885DGKA 1936/4885PAM 2264/4885
US-20220024980-A1 LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF PGLS, LGALS3BP, LNPEP TSHR 3549/4885DGKA 1220/4885PAM 261/4885
US-11857597-B2 Lipo-glycopeptide cleavable derivatives and uses thereof LGALS3BP, LGMN, LNPEP TSHR 3830/4885DGKA 1155/4885PAM 269/4885
US-20200199063-A1 TRPV1 Modulator Compounds TRPV1, TRPA1, TRPV3 TSHR 530/4885DGKA 1936/4885PAM 2264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.