Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 4/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 5/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17609284 | 0.88 | UTRN (0.40) | UTRNHDAC6CYP1A2AHRPTPN2 | |
| SCHEMBL17231823 | 0.87 | UTRN (0.39) | UTRNHDAC6CYP1A2AHRPTPN2 | |
| SCHEMBL17231828 | 0.87 | UTRN (0.43) | UTRNHDAC6CYP1A2AHRPTPN2 | |
| SCHEMBL29431588 | 0.86 | UTRN (0.43) | UTRNHDAC6CYP1A2AHRPTPN2 | |
| SCHEMBL15847456 | 0.86 | UTRN (0.43) | UTRNHDAC6CYP1A2AHRPTPN2 | |
| SCHEMBL20607635 | 0.85 | DDR1 (0.35) | DDR1 | |
| SCHEMBL15858543 | 0.85 | UTRN (0.38) | UTRNHDAC6CYP1A2AHRPTPN2 | |
| SCHEMBL29431627 | 0.85 | UTRN (0.38) | UTRNHDAC6CYP1A2AHRPTPN2 | |
| SCHEMBL17231825 | 0.84 | UTRN (0.38) | UTRNHDAC6CYP1A2AHRPTPN2 | |
| SCHEMBL29431577 | 0.83 | UTRN (0.39) | UTRNHDAC6CYP1A2AHRPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-20 | — | — | US | claimed |
| CN-106715428-B | Pesticidally active tetracyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-20 | — | — | US | disclosed |
| US-10435401-B2 | Pesticidally active tetracyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-08 | — | — | US | disclosed |
| EP-3194394-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-09 | — | — | EP | disclosed |
| US-20160099425-A1 | HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS | UNIVERSAL DISPLAY CORPORATION | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160099425-A1 | HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS | JUND, DRD2, DRD1 | UTRN 3971/4885DDR1 4079/4885HDAC6 3238/4885 |
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | UTRN 4095/4885DDR1 4290/4885HDAC6 357/4885 |
| US-10435401-B2 | Pesticidally active tetracyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTO1 | UTRN 4289/4885DDR1 4051/4885HDAC6 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.