SCHEMBL17231823

SCHEMBL17231823

CCS(=O)(=O)c1cc(C(F)(F)F)cnc1-c1nc2cc(SC)ccc2o1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ UTRN P46939 5/20 0.39
▸ HDAC6 Q9UBN7 2/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ AHR P35869 1/20 0.37
▸ PTPN2 P17706 6/20 0.37
▸ PTPN1 P18031 6/20 0.37
▸ PTPN5 P54829 6/20 0.37
▸ HSPD1 P10809 3/20 0.37
▸ HSPE1 P61604 3/20 0.37
▸ CEPT1 Q9Y6K0 1/20 0.37
▸ MEN1 O00255 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ HDAC3 O15379 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ HDAC2 Q92769 1/20 0.34
▸ HDAC8 Q9BY41 1/20 0.34
▸ F2RL3 Q96RI0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431627 0.92 UTRN (0.38) UTRNHDAC6CYP1A2AHRPTPN2
SCHEMBL15858543 0.92 UTRN (0.38) UTRNHDAC6CYP1A2AHRPTPN2
SCHEMBL17609284 0.87 UTRN (0.40) UTRNHDAC6CYP1A2AHRPTPN2
SCHEMBL20607634 0.87 UTRN (0.40) UTRNHDAC6CYP1A2AHRPTPN2
SCHEMBL17231828 0.86 UTRN (0.43) UTRNHDAC6CYP1A2AHRPTPN2
SCHEMBL29431588 0.85 UTRN (0.43) UTRNHDAC6CYP1A2AHRPTPN2
SCHEMBL15847456 0.85 UTRN (0.43) UTRNHDAC6CYP1A2AHRPTPN2
SCHEMBL17231825 0.83 UTRN (0.38) UTRNHDAC6CYP1A2AHRPTPN2
SCHEMBL17231824 0.82 UTRN (0.38) UTRNHDAC6PTPN2PTPN1PTPN5
SCHEMBL29431577 0.82 UTRN (0.39) UTRNHDAC6CYP1A2AHRPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 — — US disclosed
US-9854805-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 — — US disclosed
US-9723835-B2 Pest control composition and method for controlling pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 — — US disclosed
US-9615580-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-11 — — US disclosed
US-9549559-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-24 — — US disclosed
US-20150366207-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-24 — — US disclosed
US-20150366208-A1 METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-24 — — US disclosed
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150359222-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150366207-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS NIT2, CRY1, CNPY2 UTRN 3733/4885HDAC6 1429/4885CYP1A2 71/4885
US-20150359222-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS TH, TCOF1, BLVRB UTRN 1134/4885HDAC6 2664/4885CYP1A2 1010/4885
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL AFF1, AFF2, PYM1 UTRN 4827/4885HDAC6 984/4885CYP1A2 105/4885
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS PNPO, NAMPT, NNT UTRN 4825/4885HDAC6 1471/4885CYP1A2 217/4885
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST ABAT, PNPO, GABBR1 UTRN 4618/4885HDAC6 3299/4885CYP1A2 770/4885
US-20150366208-A1 METHOD FOR CONTROLLING PESTS BROX, RNGTT, NOS1 UTRN 4222/4885HDAC6 1064/4885CYP1A2 317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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