Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619540 | 0.86 | L3MBTL1 (0.42) | RAB9ASMN1; SMN2HPGDNPC1KMT2A | |
| SCHEMBL20619666 | 0.81 | AVPR2 (0.48) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL19078674 | 0.78 | RAB9A (0.51) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL20619653 | 0.77 | RAB9A (0.43) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL20620133 | 0.77 | RAB9A (0.41) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL20619512 | 0.77 | RAB9A (0.41) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL8820844 | 0.74 | AVPR2 (0.54) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL7351134 | 0.74 | AVPR2 (0.59) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL8556725 | 0.74 | AVPR2 (0.48) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL8559469 | 0.73 | AVPR2 (0.65) | AVPR2AVPR1ARAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091501-B2 | Heterocyclic compounds as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20190002479-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2019-01-03 | — | — | US | disclosed |
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091501-B2 | Heterocyclic compounds as RSV inhibitors | SIRT1, FURIN, SIRT5 | AVPR2 1011/4885AVPR1A 1410/4885RAB9A 575/4885 |
| US-20190002479-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | SIRT1, FURIN, SIRT5 | AVPR2 1011/4885AVPR1A 1410/4885RAB9A 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.