Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.41 |
| ▸ | PCNA | P12004 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598746 | 0.83 | BCHE (0.36) | TRPV1ERCC1ERCC4PCNAMAPT | |
| SCHEMBL20599212 | 0.83 | CYP1A2 (0.46) | KDM4ELMNA | |
| SCHEMBL20622007 | 0.82 | RPS6KB2 (0.45) | KDM4EALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL20598275 | 0.76 | PLA2G4A (0.41) | KDM4ELMNA | |
| SCHEMBL5693424 | 0.75 | LMNA (0.51) | MAPTKDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL18932566 | 0.74 | LMNA (0.43) | TRPV1ERCC1ERCC4MAPTKDM4E | |
| SCHEMBL14348868 | 0.74 | LMNA (0.48) | TRPV1ERCC1ERCC4MAPTKDM4E | |
| SCHEMBL18392440 | 0.74 | ERCC1 (0.60) | TRPV1ERCC1ERCC4PCNAMAPT | |
| SCHEMBL8160946 | 0.74 | KMT2A (0.55) | CNR2PCNAMAPTKDM4EALDH1A1 | |
| SCHEMBL4453981 | 0.74 | NPC1 (0.52) | KDM4EALDH1A1POLBLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975040-B2 | Hydroxyphenyl naphthotriazoles as polymerizable blockers of high energy light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20190002415-A1 | HYDROXYPHENYL NAPHTHOTRIAZOLES AS POLYMERIZABLE BLOCKERS OF HIGH ENERGY LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975040-B2 | Hydroxyphenyl naphthotriazoles as polymerizable blockers of high energy light | HRH3, HMGB3, CRYAB | CNR2 2272/4885TRPV1 2530/4885ERCC1 71/4885 |
| US-20190002415-A1 | HYDROXYPHENYL NAPHTHOTRIAZOLES AS POLYMERIZABLE BLOCKERS OF HIGH ENERGY LIGHT | HRH3, HMGB3, CRYAB | CNR2 2272/4885TRPV1 2530/4885ERCC1 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.