Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693424 | 0.93 | LMNA (0.51) | NPC1LMNARAB9APTPN1KDM4E | |
| SCHEMBL20599212 | 0.86 | CYP1A2 (0.46) | RPS6KB2NPC1LMNARAB9AKDM4E | |
| SCHEMBL9580856 | 0.85 | EGFR (0.43) | NPC1LMNARAB9AKDM4EPOLB | |
| SCHEMBL20598749 | 0.83 | APP (0.45) | NPC1LMNARAB9AKDM4EPOLB | |
| SCHEMBL5693442 | 0.82 | FFAR4 (0.40) | NPC1LMNARAB9AKDM4EPOLB | |
| SCHEMBL20598275 | 0.82 | PLA2G4A (0.41) | RPS6KB2NPC1LMNARAB9AKDM4E | |
| SCHEMBL20622005 | 0.82 | CNR2 (0.42) | LMNAKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL20598746 | 0.78 | BCHE (0.36) | LMNAKDM4EPOLBAPPALDH1A1 | |
| SCHEMBL31361788 | 0.78 | NPC1 (0.49) | NPC1LMNARAB9AKDM4EPOLB | |
| Naphthalene SCHEMBL5397697 | 0.78 | APP (0.59) | LMNAPTPN1KDM4EPOLBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975040-B2 | Hydroxyphenyl naphthotriazoles as polymerizable blockers of high energy light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20190002415-A1 | HYDROXYPHENYL NAPHTHOTRIAZOLES AS POLYMERIZABLE BLOCKERS OF HIGH ENERGY LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975040-B2 | Hydroxyphenyl naphthotriazoles as polymerizable blockers of high energy light | HRH3, HMGB3, CRYAB | RPS6KB2 4314/4885NPC1 3496/4885LMNA 1100/4885 |
| US-20190002415-A1 | HYDROXYPHENYL NAPHTHOTRIAZOLES AS POLYMERIZABLE BLOCKERS OF HIGH ENERGY LIGHT | HRH3, HMGB3, CRYAB | RPS6KB2 4314/4885NPC1 3496/4885LMNA 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.