Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29584517 | 1.00 | NPC1 (0.71) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| Indole SCHEMBL2062067 | 0.89 | NPC1 (0.57) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| SCHEMBL5053299 | 0.86 | NPC1 (0.87) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| 2-Phenyl-1H-Indole SCHEMBL29363616 | 0.84 | NPC1 (1.00) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| SCHEMBL28416625 | 0.84 | NPC1 (0.83) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| 2-Phenyl-1H-Indole SCHEMBL341378 | 0.84 | NPC1 (1.00) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| 2-Phenyl-1H-Indole SCHEMBL29642295 | 0.82 | NPC1 (0.96) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| 2-Phenyl-1H-Indole SCHEMBL11652520 | 0.82 | NPC1 (0.96) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| 2-Phenyl-1H-Indole SCHEMBL28371904 | 0.82 | NPC1 (0.96) | NPC1RAB9ACYP19A1KDM4EMAPT | |
| 2-Phenyl-1H-Indole SCHEMBL6529483 | 0.82 | NPC1 (0.96) | NPC1RAB9ACYP19A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023162653-A1 | RESIST UNDERLAYER FILM FORMATION COMPOSITION | 日産化学株式会社 | 2023-08-31 | — | — | WO | disclosed |
| CN-113646301-A | Antibacterial compounds and methods of use thereof | 深圳大学 | 2021-11-12 | — | — | CN | disclosed |
| US-10023594-B2 | Zwitterionic zinc(II) carboxylate compounds and their use | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (MO) | 2018-07-17 | — | — | US | disclosed |
| US-10023594-B2 | Zwitterionic zinc(II) carboxylate compounds and their use | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (MO) | 2018-07-17 | — | — | US | disclosed |
| US-20180057512-A1 | ZWITTERIONIC ZINC(II) CARBOXYLATE COMPOUNDS AND THEIR USE | SOUTHERN MEDICAL UNIVERSITY (CN) | 2018-03-01 | — | — | US | disclosed |
| US-20180057512-A1 | ZWITTERIONIC ZINC(II) CARBOXYLATE COMPOUNDS AND THEIR USE | SOUTHERN MEDICAL UNIVERSITY (CN) | 2018-03-01 | — | — | US | disclosed |
| US-8148392-B2 | 2-indolyl imidazo [4,5-d] phenanthroline derivatives and their use in the treatment of cancer | LORUS THERAPEUTICS INC. (CA) | 2012-04-03 | — | — | US | disclosed |
| US-8148392-B2 | 2-indolyl imidazo [4,5-d] phenanthroline derivatives and their use in the treatment of cancer | LORUS THERAPEUTICS INC. (CA) | 2012-04-03 | — | — | US | disclosed |
| US-8148392-B2 | 2-indolyl imidazo [4,5-d] phenanthroline derivatives and their use in the treatment of cancer | LORUS THERAPEUTICS INC. (CA) | 2012-04-03 | — | — | US | disclosed |
| WO-2011121629-A1 | INDOLIC DERIVATIVES AND USE THEREOF IN MEDICAL FIELD | UNIVERSITA' DEGLI STUDI DL ROMA "LA SAPIENZA" (IT) | 2011-10-06 | — | — | WO | disclosed |
| US-20010020095-A1 | Indane or dihydroindole derivatives | H. LUNDBECK A/S (DK) | 2001-09-06 | — | — | US | disclosed |
| US-6262087-B1 | HAVE HIGH AFFINITY FOR D4 RECEPTORS; USEFUL IN THE TREATMENT OF CERTAIN PSYCHIATRIC AND NEUROLOGIC DISORDERS, INCLUDING PSYCHOSIS, DEPRESSION AND ANXIETY. | H. LUNDBECK A/S (DK) | 2001-07-17 | — | — | US | disclosed |
| EP-1077213-A2 | Inhibition of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6046215-A | A PIPERIDINYLBENZOTHIOPHENES USEFUL FOR TRATING BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 2000-04-04 | — | — | US | disclosed |
| CN-1246117-A | 1, 2-indane or indoline derivatives | LUNDBECK & CO AS H (DK) | 2000-03-01 | — | — | CN | disclosed |
| EP-0946542-A1 | INDANE OR DIHYDROINDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 1999-10-06 | — | — | EP | disclosed |
| US-5846982-A | Inhibition of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1998028293-A1 | INDANE OR DIHYDROINDOLE DERIVATIVES | H.LUNDBECK A/S (DK) | 1998-07-02 | — | — | WO | disclosed |
| WO-1997047302-A1 | INHIBITION OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |
| EP-0812826-A1 | 1H-indole and benzo(b)thiophene derivatives with 4-(1,2,3,6-tetra:hydro:pyridinyl)- and 4-piperidinyl-groups bound to the heterocyclic ring as inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020095-A1 | Indane or dihydroindole derivatives | HTR4, GPR4, GPR174 | NPC1 1119/4885RAB9A 2677/4885CYP19A1 474/4885 |
| US-10023594-B2 | Zwitterionic zinc(II) carboxylate compounds and their use | ZC3HAV1, ZC3HAV1L, ZKSCAN2 | NPC1 3017/4885RAB9A 4045/4885CYP19A1 4259/4885 |
| US-20180057512-A1 | ZWITTERIONIC ZINC(II) CARBOXYLATE COMPOUNDS AND THEIR USE | ZC3HAV1, ZC3HAV1L, ZKSCAN2 | NPC1 3017/4885RAB9A 4045/4885CYP19A1 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.