Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235427 | 0.88 | TDP1 (0.49) | LMNAMRGPRX4TDP1NPC1RAB9A | |
| SCHEMBL8837400 | 0.84 | LMNA (0.52) | LMNAMRGPRX4SRCTDP1CHRM1 | |
| SCHEMBL9834120 | 0.83 | LMNA (0.55) | LMNASRCGPR84TDP1L3MBTL1 | |
| SCHEMBL11330499 | 0.82 | TDP1 (0.46) | LMNAMRGPRX4TDP1NPC1RAB9A | |
| SCHEMBL9139773 | 0.81 | SRC (0.57) | LMNASRCTDP1HTTL3MBTL1 | |
| SCHEMBL6330127 | 0.80 | TDP1 (0.45) | LMNAMRGPRX4TDP1NPC1RAB9A | |
| Fluoride SCHEMBL31047193 | 0.80 | SRC (0.55) | LMNASRCTDP1HTTL3MBTL1 | |
| Chlorobenzene SCHEMBL27257873 | 0.79 | SRC (0.59) | SRCGPR84TDP1HTTL3MBTL1 | |
| SCHEMBL9494492 | 0.79 | TDP1 (0.44) | LMNAMRGPRX4TDP1NPC1RAB9A | |
| SCHEMBL4372630 | 0.78 | INPPL1 (0.52) | LMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020095034-A1 | Imipenem production process | ACS DOBFAR S.P.A. (IT) | 2002-07-18 | — | — | US | claimed |
| US-20120095210-A1 | PROCESS FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2012-04-19 | — | — | US | disclosed |
| US-8148520-B2 | Process for the preparation of beta-lactam antibiotic meropenem trihydrate | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2012-04-03 | — | — | US | disclosed |
| US-20090264643-A1 | Process for The Preparation of Beta-Lactam Antibiotic | ORCHID CHEMICALS & PHARMACEUTICALS LTD. | 2009-10-22 | — | — | US | disclosed |
| EP-1934221-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTIC | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007031858-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTIC | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2007-03-22 | — | — | WO | disclosed |
| US-20020095034-A1 | Imipenem production process | ACS DOBFAR S.P.A. (IT) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264643-A1 | Process for The Preparation of Beta-Lactam Antibiotic | MAN2B2, SAMM50, MANBA | LMNA 1272/4885MRGPRX4 4140/4885SRC 4696/4885 |
| US-20020095034-A1 | Imipenem production process | IMPDH1, TMEM165, ICMT | LMNA 4109/4885MRGPRX4 4663/4885SRC 4841/4885 |
| US-20120095210-A1 | PROCESS FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTIC | MGAM, BPGM, MPDU1 | LMNA 1529/4885MRGPRX4 2352/4885SRC 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.