Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18618549 | 0.84 | ALDH1A1 (0.46) | ABCB11ALDH1A1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL20625890 | 0.79 | ABCC9 (0.43) | ABCB11ALDH1A1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL20625930 | 0.77 | HDAC1 (0.45) | ALDH1A1HPGDHSD17B10HDAC1HDAC7 | |
| SCHEMBL2088436 | 0.70 | CETP (0.50) | ALDH1A1HPGDHDAC1HDAC7HDAC8 | |
| SCHEMBL5551553 | 0.70 | HDAC1 (0.70) | ALDH1A1CYP1A2CYP3A4HPGDHDAC1 | |
| SCHEMBL3788181 | 0.69 | HDAC1 (0.47) | HDAC1HDAC7HDAC8HDAC6JAK2 | |
| SCHEMBL22265182 | 0.67 | HDAC1 (0.72) | ALDH1A1CYP1A2CYP3A4HPGDMAOA | |
| SCHEMBL20436327 | 0.65 | ALDH1A1 (0.57) | ALDH1A1CYP1A2HPGDMAOAHSD17B10 | |
| SCHEMBL17570895 | 0.65 | CYP1A2 (0.43) | ALDH1A1CYP1A2HPGDMAPTKDM4E | |
| SCHEMBL29642615 | 0.65 | ALDH1A1 (0.42) | ABCB11ALDH1A1NR3C1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174161-B2 | Transformation of meso-lactide | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2019-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174161-B2 | Transformation of meso-lactide | RALA, LCT, LTA | ABCB11 3448/4885ALDH1A1 2306/4885NR3C1 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.