Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4125050 | 0.81 | KDM4E (0.49) | HDAC1MAPTPARP14NPC1RAB9A | |
| SCHEMBL30237970 | 0.79 | MEN1 (0.60) | HDAC1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL20625929 | 0.77 | ABCB11 (0.41) | HDAC1HDAC7HDAC8HDAC6MAPT | |
| SCHEMBL2088436 | 0.76 | CETP (0.50) | HDAC1HDAC7HDAC8HDAC6MAPT | |
| SCHEMBL18619655 | 0.76 | ABCC9 (0.48) | HDAC1MAPTTP53HTTNPC1 | |
| SCHEMBL5551553 | 0.76 | HDAC1 (0.70) | HDAC1HDAC7HDAC8HDAC6MAPT | |
| SCHEMBL3788181 | 0.74 | HDAC1 (0.47) | HDAC1HDAC7HDAC8HDAC6MAPT | |
| SCHEMBL17977237 | 0.73 | MAPT (0.57) | MAPTNPC1RAB9AKDM4EGAA | |
| SCHEMBL29418101 | 0.73 | MAPT (0.57) | MAPTNPC1RAB9AKDM4EGAA | |
| SCHEMBL455943 | 0.73 | ALDH1A1 (0.56) | MAPTMEN1KMT2AWDR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174161-B2 | Transformation of meso-lactide | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2019-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174161-B2 | Transformation of meso-lactide | RALA, LCT, LTA | HDAC1 2348/4885HDAC7 3555/4885HDAC8 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.