Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 4/20 | 0.35 |
| ▸ | PAK4 | O96013 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15016943 | 0.79 | PLK4 (0.38) | ALDH1A1TRPA1PLK4PAK4HTR2C | |
| SCHEMBL13153124 | 0.76 | KMT2A (0.46) | ALDH1A1PLK4PAK4KDM4EHTR2C | |
| SCHEMBL19966396 | 0.73 | FGFR1 (0.39) | ALDH1A1PLK4PAK4HTR2CHTR2A | |
| SCHEMBL25322760 | 0.73 | ALDH1A1 (0.40) | ALDH1A1PLK4PAK4KDM4ESMN1; SMN2 | |
| SCHEMBL24348557 | 0.73 | PLK4 (0.38) | ALDH1A1PLK4PAK4KDM4EHTR2C | |
| SCHEMBL23841035 | 0.73 | NCF1 (0.43) | ALDH1A1PLK4PAK4KDM4EPDPK1 | |
| SCHEMBL30509508 | 0.73 | ALDH1A1 (0.40) | ALDH1A1PLK4PAK4KDM4ESMN1; SMN2 | |
| SCHEMBL26661515 | 0.71 | TRPA1 (0.39) | ALDH1A1TRPA1PLK4PAK4HTR2C | |
| SCHEMBL24494919 | 0.70 | HTT (0.33) | TRPA1HTTIDO1 | |
| SCHEMBL30468824 | 0.70 | HTT (0.33) | TRPA1HTTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791137-B1 | PYRAZOLOPYRIDINE DERIVATIVES, PREPARATION PROCESS THEREFOR AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2019-01-23 | — | — | EP | claimed |